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Epidemiology of Ductal Carcinoma In Situ
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Zervoudis, Stefanos
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Univ West Attica, Dept Midwifery, Athens, Greece
Rea Matern Hosp, Breast Ctr, Athens, Greece
Rea Matern Hosp, Breast Clin, Athens, Greece Univ West Attica, Dept Midwifery, Athens, Greece
机构:
[1] Univ West Attica, Dept Midwifery, Athens, Greece
[2] Rea Matern Hosp, Breast Ctr, Athens, Greece
[3] Rea Matern Hosp, Breast Clin, Athens, Greece
来源:
关键词:
ductal carcinoma in situ;
breast;
epidemiology;
incidence;
risk factors;
POSTMENOPAUSAL HORMONE-THERAPY;
RISK-FACTORS;
BREAST-CANCER;
CIGARETTE-SMOKING;
COHORT;
TUMOR;
DCIS;
D O I:
10.21614/chirurgia.116.5.Suppl.S15
中图分类号:
R61 [外科手术学];
学科分类号:
摘要:
Ductal carcinoma in situ (DCIS) is thought to be a direct precursor of most cases of breast cancer and its incidence increases with age. However, the globally impressive rise of DCIS cases is probably an epidemiologic "artifact" that is mainly attributed to the establishment of screening mammography in developed countries. Furthermore, considering that usually there are no clinical findings of the disease, the initial detection of DCIS is a mammographic "event" in most cases. The risk factors for DCIS are similar to those for invasive cancer including, among others, deleterious mutations in the BRCA genes, family history of breast cancer, nulliparity, late age at first birth, increased breast density, personal history of benign breast disease, and postmenopausal obesity.
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页码:S15 / S21
页数:7
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共 45 条
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