Results of Surgical Treatment of Schwannomas Arising from Extremities

被引:35
作者
Gosk, Jerzy [1 ]
Gutkowska, Olga [1 ]
Urban, Maciej [1 ]
Wnukiewicz, Witold [1 ]
Reichert, Pawel [1 ]
Ziolkowski, Piotr [2 ]
机构
[1] Wroclaw Med Univ, Dept Traumatol Clin Traumatol & Hand Surg, PL-50556 Wroclaw, Poland
[2] Wroclaw Med Univ, Dept Pathomorphol, Div Pathomorphol, PL-50368 Wroclaw, Poland
关键词
PERIPHERAL-NERVE TUMORS; NEURAL SHEATH TUMORS; PLEXIFORM SCHWANNOMA; SYMPTOMS; ANCIENT; HAND;
D O I
10.1155/2015/547926
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Schwannomas are benign neoplasms derived from Schwann cells. In this work, we present our experience in operative management of schwannomas and analyse results of treatment. Clinical material consisted of 34 patients, in whom 44 schwannomas located in extremities were excised between 1985 and 2013. Thirty-five tumours originated from major peripheral nerves and 9 from small nerve branches. Postoperatively, in the first group of tumours, pain resolved in 100%, paresthesias in 83.3%, and Hoffmann-Tinel sign in 91.6% of the patients. Improvement in motor function was noted in 28.5% of the cases, in sensory function: complete in 70%, and partial in 15%. The most frequently affected major peripheral nerves were the ulnar (11 tumours) and median (5 tumours) nerves. Schwannomas originating from small nerve branches were removed without identification of the site of origin. After their resection, definitive healing was achieved. Conclusions. (1) Schwannomas located in extremities arise predominantly from major peripheral nerves, most commonly the ulnar and median nerves. (2) Gradual tumour growth causes exacerbation of compression neuropathy, creating an indication for surgery. (3) In most cases, improvement in peripheral nerve function after excision of schwannoma is achieved. (4) The risk of new permanent postoperative neurological deficits is low.
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页数:8
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