Analytical techniques for monitoring of toluene and xylene exposure biomarkers hippuric acid and methylhippuric acid in human urine samples

被引：6

作者：

Shan, Xiaoyue ^{[1
]}

Zhang, Lei ^{[1
]}

Ye, Haipeng ^{[1
]}

Shao, Ji ^{[1
]}

Shi, Yanpeng ^{[1
]}

Tan, Siwei ^{[1
]}

Zhang, Ling ^{[1
]}

Su, Kewen ^{[1
]}

机构：

[1] Hangzhou Occupat Dis Prevent & Control Hosp, Hangzhou 310014, Peoples R China

来源：

BIOANALYSIS | 2021年 / 13卷 / 20期

关键词：

analytical techniques; hippuric acid; methyl hippuric acid; toluene; urine; xylene; ELECTROMEMBRANE EXTRACTION; OCCUPATIONAL-EXPOSURE; HPLC-DAD; BENZENE; METABOLITES; ETHYLBENZENE; QUANTIFICATION; BTEX; SPECTROMETRY; POLLUTANTS;

D O I：

10.4155/bio-2021-0180

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Quantification of hippuric acid and methylhippuric acid in human urine matrices provides information on the toluene and xylene exposure conditions. High performance liquid chromatography coupled with UV detection is the preferable technique for hippuric acid and methylhippuric acid detection in human urine. This study was conducted to present analytical techniques developed for monitoring of hippuric acid and methylhippuric acid in human urine matrices during 2016-2021.

引用

页码：1569 / 1584

页数：16

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