Pseudomonas aeruginosa Alginate Benefits Staphylococcus aureus?

被引：4

作者：

Schurr, Michael J. ^{[1
]}

机构：

[1] Univ Colorado, Dept Immunol & Microbiol, Anschutz Med Campus, Aurora, CO 80045 USA

来源：

JOURNAL OF BACTERIOLOGY | 2020年 / 202卷 / 08期

关键词：

coinfection; Pseudomonas aeruginosa; Staphylococcus aureus; cystic fibrosis; CYSTIC-FIBROSIS; MUCOID PSEUDOMONAS; REGULATED PROTEOLYSIS; CONVERSION; ALGU; BIOSYNTHESIS; BIOFILMS; STRESS; EXOPOLYSACCHARIDE; ANTIBIOTICS;

D O I：

10.1128/JB.00040-20

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In this issue of Journal of Bacteriology, Price et al. show that the Pseudomonas aeruginosa-produced exopolysaccharide alginate protects Staphylococcus aureus by dampening the expression of P. aeruginosa virulence products that usually inhibit S. aureus respiration and cell membrane integrity when the two organisms compete in other environments (C. E. Price, D. G. Brown, D. H. Limoli, V. V. Phelan, and G. A. O'Toole, J Bacteriol 202:e00559-19, 2020, https://doi.org/10.1128/jb.00559-19). This is the first report that exogenously added alginate affects P. aeruginosa competition and provides a partial explanation for S. aureus and P. aeruginosa coinfections in cystic fibrosis.

引用

页数：4

共 38 条

[1] Clinical outcomes associated with Staphylococcus aureus and Pseudomonas aeruginosa airway infections in adult cystic fibrosis patients [J].

Ahlgren, Heather G. ;

Benedetti, Andrea ;

Landry, Jennifer S. ;

Bernier, Joanie ;

Matouk, Elias ;

Radzioch, Danuta ;

Lands, Larry C. ;

Rousseau, Simon ;

Nguyen, Dao .

BMC PULMONARY MEDICINE, 2015, 15

[2] Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis Airways Influences Virulence of Staphylococcus aureus In Vitro and Murine Models of Co-Infection [J].

Baldan, Rossella ;

Cigana, Cristina ;

Testa, Francesca ;

Bianconi, Irene ;

De Simone, Maura ;

Pellin, Danilo ;

Di Serio, Clelia ;

Bragonzi, Alessandra ;

Cirillo, Daniela M. .

PLOS ONE, 2014, 9 (03)

[3] FUNCTIONAL-ROLE OF MUCOID EXOPOLYSACCHARIDE (ALGINATE) IN ANTIBIOTIC-INDUCED AND POLYMORPHONUCLEAR LEUKOCYTE-MEDIATED KILLING OF PSEUDOMONAS-AERUGINOSA [J].

BAYER, AS ;

SPEERT, DP ;

PARK, S ;

TU, J ;

WITT, M ;

NAST, CC ;

NORMAN, DC .

INFECTION AND IMMUNITY, 1991, 59 (01) :302-308

[4] Sequence diversity of the mucABD locus in Pseudomonas aeruginosa isolates from patients with cystic fibrosis [J].

Bragonzi, Alessandra ;

Wiehlmann, Lutz ;

Klockgether, Jens ;

Cramer, Nina ;

Worlitzsch, Dieter ;

Doering, Gerd ;

Tuemmler, Burkhard .

MICROBIOLOGY-SGM, 2006, 152 :3261-3269

[5] An In Vivo Polymicrobial Biofilm Wound Infection Model to Study Interspecies Interactions [J].

Dalton, Trevor ;

Dowd, Scot E. ;

Wolcott, Randall D. ;

Sun, Yan ;

Watters, Chase ;

Griswold, John A. ;

Rumbaugh, Kendra P. .

PLOS ONE, 2011, 6 (11)

[6] Biofilms: Survival mechanisms of clinically relevant microorganisms [J].

Donlan, RM ;

Costerton, JW .

CLINICAL MICROBIOLOGY REVIEWS, 2002, 15 (02) :167-+

[7] Coculture of Staphylococcus aureus with Pseudomonas aeruginosa Drives S-aureus towards Fermentative Metabolism and Reduced Viability in a Cystic Fibrosis Model [J].

Filkins, Laura M. ;

Graber, Jyoti A. ;

Olson, Daniel G. ;

Dolben, Emily L. ;

Lynd, Lee R. ;

Bhuju, Sabin ;

O'Toole, George A. .

JOURNAL OF BACTERIOLOGY, 2015, 197 (14) :2252-2264

[8] CLONING OF GENES FROM MUCOID PSEUDOMONAS-AERUGINOSA WHICH CONTROL SPONTANEOUS CONVERSION TO THE ALGINATE PRODUCTION PHENOTYPE [J].

FLYNN, JL ;

OHMAN, DE .

JOURNAL OF BACTERIOLOGY, 1988, 170 (04) :1452-1460

[9] Cellular organization of siderophore biosynthesis in Pseudomonas aeruginosa: Evidence for siderosomes [J].

Gasser, Veronique ;

Guillon, Laurent ;

Cunrath, Olivier ;

Schalk, Isabelle J. .

JOURNAL OF INORGANIC BIOCHEMISTRY, 2015, 148 :27-34

[10] Role of Exopolysaccharides in Pseudomonas aeruginosa Biofilm Formation and Architecture [J].

Ghafoor, Aamir ;

Hay, Iain D. ;

Rehm, Bernd H. A. .

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2011, 77 (15) :5238-5246

← 1 2 3 4 →