NMR Studies of Purines

被引：18

作者：

Dracinsky, Martin ^{[1
]}

Pohl, Radek ^{[1
]}

机构：

[1] Acad Sci Czech Republ, Inst Organ Chem & Biochem, Prague, Czech Republic

来源：

ANNUAL REPORTS ON NMR SPECTROSCOPY, VOL 82 | 2014年 / 82卷

关键词：

Purines; NMR spectroscopy; Chemical shifts; DFT calculations; Tautomerism; Hydrogen bonding; Base pairing; Protonation; Metal ions; SPIN COUPLING-CONSTANTS; SOLID-STATE NMR; NUCLEIC-ACID BASES; ACYCLIC NUCLEOSIDE PHOSPHONATES; PROTON-MAGNETIC-RESONANCE; CHEMICAL-SHIFT TENSORS; X-RAY STRUCTURES; C-H ARYLATION; FUNCTIONAL THEORY CALCULATIONS; ELECTRON DEFORMATION DENSITY;

D O I：

10.1016/B978-0-12-800184-4.00002-3

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The experimental NMR methods and theoretical calculations of NMR parameters used in the studies of purine derivatives are reviewed. The first part of this chapter brings an overview of the experimental techniques that are commonly used for hydrogen, carbon and nitrogen NMR signal detection and assignment, followed by a detailed discussion of the influence of purine substitution on NMR parameters. The applications of solid-state NMR methods and the calculations of chemical shifts and indirect coupling constants of purines are also reviewed. The second part of this chapter summarises recent applications (since 2005) of these techniques in the studies of purine structure and interactions.

引用

页码：59 / 113

页数：55

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