Ring closing metathesis of vinyl glycine derivatives

被引:32
作者
Campagne, JM [1 ]
Ghosez, L [1 ]
机构
[1] Univ Catholique Louvain, Lab Chim Organ Synth, B-1348 Louvain, Belgium
关键词
D O I
10.1016/S0040-4039(98)01270-2
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Ring closing metathesis of vinyl glycine derivatives using Grubbs' ruthenium catalyst has been performed successfully. The reaction works well with N-allyl amides derived from N-protected vinyl glycines. The use ol: a trityl protecting group allows the reaction to be performed successfully with the otherwise unreactive N-allyl vinyl glycine ester. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:6175 / 6178
页数:4
相关论文
共 21 条
[1]  
Armstrong SK, 1998, J CHEM SOC PERK T 1, P371
[2]   Highly functionalised monocyclic and bicyclic beta-lactams via alkene metathesis [J].
Barrett, AGM ;
Baugh, SPD ;
Gibson, VC ;
Giles, MR ;
Marshall, EL ;
Procopiou, PA .
CHEMICAL COMMUNICATIONS, 1997, (02) :155-156
[3]   Well-defined ruthenium olefin metathesis catalysts: Mechanism and activity [J].
Dias, EL ;
Nguyen, ST ;
Grubbs, RH .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (17) :3887-3897
[4]  
FU GC, 1992, J AM CHEM SOC, V114, P7314
[5]   Macrocycles by ring-closing metathesis [J].
Furstner, A ;
Langemann, K .
SYNTHESIS-STUTTGART, 1997, (07) :792-&
[6]   Total syntheses of (+)-ricinelaidic acid lactone and of (-)-gloeosporone based on transition-metal-catalyzed C-C bond formations [J].
Furstner, A ;
Langemann, K .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (39) :9130-9136
[7]   New potential access to ethylenic pseudodipeptides through catalytic alkene metathesis [J].
GarroHelion, F ;
Guibe, F .
CHEMICAL COMMUNICATIONS, 1996, (05) :641-642
[8]   Recent advances in olefin metathesis and its application in organic synthesis [J].
Grubbs, RH ;
Chang, S .
TETRAHEDRON, 1998, 54 (18) :4413-4450
[9]   Synthesis of conformationally restricted serine derivatives through ruthenium(II)-catalyzed ring closing metathesis. [J].
Hammer, K ;
Undheim, K .
TETRAHEDRON, 1997, 53 (16) :5925-5936
[10]  
Huwe CM, 1996, SYNLETT, P65