Direct gas chromatographic separation of drug racemates

被引:0
作者
Schleuder, M [1 ]
Durrbeck, A [1 ]
Jira, T [1 ]
机构
[1] Univ Greifswald, Inst Pharm, D-17489 Greifswald, Germany
来源
PHARMAZIE | 1998年 / 53卷 / 06期
关键词
D O I
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中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
For inspection of the direct separability of synthetic drug racemates through GC/MS a uniform scheme is proposed and checked with 35 drugs and two cyclodextrin capillary columns. All investigated analytes vaporized without decomposition, 26 of them are separable in the enantiomers, among them 10 with separation to the baseline and 14 with CO-NH-structure.
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页码:381 / 386
页数:6
相关论文
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