Polar expeditions - provisioning the centrosome for mitosis

被引：110
作者：
Blagden, SP [1 ]
Glover, DM [1 ]
机构：
[1] Univ Cambridge, Dept Genet, Canc Res UK Cell Cycle Genet Res Grp, Cambridge CB2 3EH, England
来源：
NATURE CELL BIOLOGY | 2003年 / 5卷 / 06期
关键词：
D O I：
10.1038/ncb0603-505
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
It is now clear that both centrioles and their surrounding pericentriolar material (PCM) are capable of self-assembly. Whereas centrioles are normally duplicated during G1-S phase, PCM components may be loaded onto centrosomes in both a microtubule-dependent and -independent manner at all stages of the cell cycle. Centrosomes enlarge dramatically after mitotic entry, when both Aurora A and Polo-like kinases cooperate to recruit additional gamma-tubulin ring complexes and microtubule-associated proteins to assist spindle formation.
引用
收藏
页码：505 / 511
页数：7
相关论文
共 97 条
[1]   FORMATION OF BASAL BODIES (CENTRIOLES) IN RHESUS MONKEY OVIDUCT [J].
ANDERSON, RG ;
BRENNER, RM .
JOURNAL OF CELL BIOLOGY, 1971, 50 (01) :10-&
[2]   Abnormal spindle protein, asp, and the integrity of mitotic centrosomal microtubule organizing centers [J].
Avides, MD ;
Glover, DM .
SCIENCE, 1999, 283 (5408) :1733-1735
[3]   Polo kinase and Asp are needed to promote the mitotic organizing activity of centrosomes [J].
Avides, MD ;
Tavares, A ;
Glover, DM .
NATURE CELL BIOLOGY, 2001, 3 (04) :421-424
[4]  
Balczon R, 1999, CELL MOTIL CYTOSKEL, V42, P60, DOI 10.1002/(SICI)1097-0169(1999)42:1<60::AID-CM6>3.3.CO
[5]  
2-Z
[6]   Drosophila dd4 mutants reveal that γTURC is required to maintain juxtaposed half spindles in spermatocytes [J].
Barbosa, V ;
Gatt, M ;
Rebollo, E ;
Gonzalez, C ;
Glover, DM .
JOURNAL OF CELL SCIENCE, 2003, 116 (05) :929-941
[7]   Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization [J].
Barbosa, V ;
Yamamoto, RR ;
Henderson, DS ;
Glover, DM .
GENES & DEVELOPMENT, 2000, 14 (24) :3126-3139
[8]   Drosophila aurora-A is required for centrosome maturation and actin-dependent asymmetric protein localization during mitosis [J].
Berdnik, D ;
Knoblich, JA .
CURRENT BIOLOGY, 2002, 12 (08) :640-647
[9]   Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells [J].
Bobinnec, Y ;
Khodjakov, A ;
Mir, LM ;
Rieder, CL ;
Eddé, B ;
Bornens, M .
JOURNAL OF CELL BIOLOGY, 1998, 143 (06) :1575-1589
[10]   ASPM is a major determinant of cerebral cortical size [J].
Bond, J ;
Roberts, E ;
Mochida, GH ;
Hampshire, DJ ;
Scott, S ;
Askham, JM ;
Springell, K ;
Mahadevan, M ;
Crow, YJ ;
Markham, AF ;
Walsh, CA ;
Woods, CG .
NATURE GENETICS, 2002, 32 (02) :316-320
12345678910