Feasibility of Transanal Local Excision Following Chemoradiation for Lower Rectal Cancer

被引：0
作者：
Tokunaga, Takuya [1 ]
Nishi, Masaaki [1 ]
Higashijima, Jun [1 ]
Yoshikawa, Kozo [1 ]
Kashihara, Hideya [1 ]
Takasu, Chie [1 ]
Ishikawa, Daichi [1 ]
Bando, Yoshimi [2 ]
Shimada, Mitsuo [1 ]
机构：
[1] Tokushima Univ, Dept Surg, Kuramoto, Japan
[2] Tokushima Univ, Dept Pathol, Kuramoto, Japan
来源：
ANTICANCER RESEARCH | 2017年 / 37卷 / 10期
关键词：
Chemoradiation therapy; local excision; total mesorectal excision; disease-free survival; overall survival; clinical complete response; low anterior resection; NEOADJUVANT CHEMORADIOTHERAPY; PREOPERATIVE RADIOTHERAPY; RESECTION;
D O I：
10.21873/anticanres.11996
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: The aim of this study was to evaluate the clinical outcome of transanal local excision for cT1/cT2 lower rectal cancer following pre-operative chemoradiation therapy (CRT). Patients and Methods: Eleven patients who underwent pre-operative CRT for cT1/cT2 lower rectal cancer were retrospectively enrolled in this study. Surgical outcomes were compared between the group that underwent trasanal local excision (TLE) (n=6) and that which underwent total mesorectal excision (TME) (n=5). Results: Regarding surgical outcomes, there were significant differences between the two groups in operative time, rate of anal preservation and post-operative hospital stay. There were no differences between the two groups in the disease-free or overall survival rates. Conclusion: The TLE following CRT had acceptable surgical outcomes. Surgeons should consider TLE following CRT for cT1/cT2 lower rectal cancer as a treatment option in selected patients.
引用
收藏
页码：5617 / 5622
页数：6
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