Alkylpotassium-Catalyzed Benzylic C-H Alkylation of Alkylarenes with Alkenes

被引：19

作者：

Sato, Io ^{[1
]}

Yamashita, Yasuhiro ^{[1
]}

Kobayashi, Shu ^{[1
]}

机构：

[1] Univ Tokyo, Dept Chem, Sch Sci, Bunkyo Ku, 7-3-1 Hongo, Tokyo 1130033, Japan

来源：

SYNTHESIS-STUTTGART | 2019年 / 51卷 / 01期

关键词：

strong base; alkylarene; alkylation; alkylpotassium; alkene; POTASSIUM TERT-BUTOXIDE; 1,4-ADDITION REACTIONS; BOND ADDITION; BASE; ARYLATION; TOLUENE; DERIVATIVES; ACTIVATION; OLEFINS; LIGHT;

D O I：

10.1055/s-0037-1610378

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Catalytic benzylic C-H alkylation reactions of alkylarenes with alkenes such as beta-substituted styrenes and vinylsilanes have been achieved by utilizing alkylpotassium as a catalyst. Various substituted toluene derivatives can be alkylated under mild reaction conditions to afford the desired functionalized hydrocarbons in moderate to high yields.

引用

页码：240 / 250

页数：11

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