A new prenylated dihydrochalcone from the leaves of Artocarpus lowii

被引：33

作者：

Jamil, Shajarahtunnur ^{[1
]}

Sirat, Hasnah Mohd ^{[1
]}

Jantan, Ibrahim ^{[2
]}

Aimi, Norio ^{[3
]}

Kitajima, Mariko ^{[3
]}

机构：

[1] UTM Skudai, Fac Sci, Dept Chem, Johor Baharu 81310, Johor, Malaysia

[2] Univ Kebangsaan Malaysia, Fac Allied Hlth Sci, Dept Pharm, Kuala Lumpur 50300, Malaysia

[3] Chiba Univ, Grad Sch Pharmaceut Sci, Chiba 2638522, Japan

来源：

JOURNAL OF NATURAL MEDICINES | 2008年 / 62卷 / 03期

关键词：

Artocarpus lowii; Moraceae; leaves; chalcone; antioxidant; DPPH; ESR;

D O I：

10.1007/s11418-008-0226-3

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A new prenylated dihydrochalcone, 2',4'-dihydroxy-4-methoxy-3'-prenyldihydrochalcone (1), along with two known compounds, 2',4',4-trihydroxy-3'-prenylchalcone (2) and 2',4-dihydroxy-3',4'-(2,2-dimethylchromene)chalcone (3) were isolated from the leaves of Artocarpus lowii. The structures of 1-3 were elucidated by spectroscopic methods and by comparison with data reported in the literature. Compounds 1-3 showed strong free radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl (DPPH) measured by electron spin resonance (ESR) spectrometry.

引用

页码：321 / 324

页数：4

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