Polymersomes in Polymersomes: Multiple Loading and Permeability Control

被引：124
作者：
Marguet, Maite [1 ,2 ]
Edembe, Lise [1 ,2 ]
Lecommandoux, Sebastien [1 ,2 ]
机构：
[1] Univ Bordeaux, IPB, ENSCBP, F-33607 Pessac, France
[2] CNRS, Lab Chim Polymeres Organ, UMR5629, Pessac, France
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 05期
关键词：
drug delivery; polymers; polymersomes; self-assembly; vesicles; VESICLES; DELIVERY; DRUG; SYSTEM;
D O I：
10.1002/anie.201106410
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Capsules in capsules: An emulsion-centrifugation method allows polymersomes in polymersomes PiPs (see picture) or polymer vesosomes to be prepared. This simple approach to generate biomimetic compartmentalized structures offers a way to encapsulate several different and even mutually incompatible active substances, thereby opening avenues in combinatory drug release and providing exquisite control of permeation properties. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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收藏
页码：1173 / 1176
页数：4
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