Morbidity and mortality after surgery for nonmalignant colorectal polyps

被引:84
作者
Peery, Anne F. [1 ]
Shaheen, Nicholas J. [1 ]
Cools, Katherine S. [2 ]
Baron, Todd H. [1 ]
Koruda, Mark [2 ]
Galanko, Joseph A. [1 ]
Grimm, Ian S. [1 ]
机构
[1] Univ N Carolina, Sch Med, Div Gastroenterol & Hepatol, Dept Med, Chapel Hill, NC USA
[2] Univ N Carolina, Sch Med, Div Gastrointestinal Surg, Dept Surg, Chapel Hill, NC USA
基金
美国国家卫生研究院;
关键词
ENDOSCOPIC MUCOSAL RESECTION; COLON-CANCER; COLONOSCOPIC POLYPECTOMY; SURGICAL RESECTION; ADVERSE EVENTS; OPEN COLECTOMY; TERM OUTCOMES; RISK-FACTORS; COST; TRIAL;
D O I
10.1016/j.gie.2017.03.1550
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Background and Aims: Despite evidence that most nonmalignant colorectal polyps can be managed endoscopically, a substantial proportion of patients with a nonmalignant colorectal polyp are still sent to surgery. Risks associated with this surgery are not well characterized. We describe 30-day postoperative morbidity and mortality and explore risk factors for adverse events in patients undergoing surgical resection for nonmalignant colorectal polyps. Methods: We analyzed data collected prospectively as part of the National Surgical Quality Improvement Program. Our analysis included 12,732 patients who underwent elective surgery for a nonmalignant colorectal polyp from 2011 through 2014. We report adverse events within 30 days of the index surgery. Modified Poisson regression was used to estimate risk ratios and 95% confidence intervals. Results: Thirty-day mortality was .7%. The risk of a major postoperative adverse event was 14%. Within 30 days of resection, 7.8% of patients were readmitted and 3.6% of patients had a second major surgery. The index surgery resulted in a colostomy in 1.8% and ileostomy in .4% of patients. Patients who had surgical resection of a nonmalignant polyp in the rectum or anal canal compared with the colon had a risk ratio of 1.58 (95% confidence interval, 1.09-2.28) for surgical site infection and 6.51 (95% confidence interval, 4.97-8.52) for ostomy. Conclusions: Surgery for anonmalignant colorectal polyp is associated with significant morbidity and mortality. Abetter understanding of the risks and benefits associated with surgical management of nonmalignant colorectal polyps will better inform discussions regarding the relative merits of management strategies.
引用
收藏
页码:243 / +
页数:10
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