Intra-Articular Leukocyte-Rich Platelet-Rich Plasma versus Intra-Articular Hyaluronic Acid in the Treatment of Knee Osteoarthritis: A Meta-Analysis of 14 Randomized Controlled Trials
被引:11
|
作者:
Peng, Yu-Ning
论文数: 0引用数: 0
h-index: 0
机构:
Chang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, TaiwanChang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, Taiwan
Peng, Yu-Ning
[1
]
Chen, Jean-Lon
论文数: 0引用数: 0
h-index: 0
机构:
Chang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, TaiwanChang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, Taiwan
Chen, Jean-Lon
[1
]
Hsu, Chih-Chin
论文数: 0引用数: 0
h-index: 0
机构:
Chang Gung Univ, Chang Gung Mem Hosp Keelung, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, TaiwanChang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, Taiwan
Hsu, Chih-Chin
[2
]
Chen, Carl P. C.
论文数: 0引用数: 0
h-index: 0
机构:
Chang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, TaiwanChang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, Taiwan
Chen, Carl P. C.
[1
]
Suputtitada, Areerat
论文数: 0引用数: 0
h-index: 0
机构:
Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Fac Med, Dept Rehabil Med, Bangkok 10330, ThailandChang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, Taiwan
Suputtitada, Areerat
[3
]
机构:
[1] Chang Gung Univ, Chang Gung Mem Hosp Linkou, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, Taiwan
[2] Chang Gung Univ, Chang Gung Mem Hosp Keelung, Dept Phys Med & Rehabil, Coll Med, Taoyuan City 33343, Taiwan
[3] Chulalongkorn Univ, King Chulalongkorn Mem Hosp, Fac Med, Dept Rehabil Med, Bangkok 10330, Thailand
(1) Background: To evaluate the clinical effects of leukocyte-rich platelet-rich plasma (LR-PRP) and hyaluronic acid (HA) injections in treating patients suffering from knee osteoarthritis (OA); (2) Methods: Randomized controlled trials (RCTs) were searched from PubMed, Web of Science, and Cochrane Library. Keywords were: platelet-rich plasma, LR-PRP, leukocyte-rich, hyaluronic acid, and knee osteoarthritis. The included RCTs were published between the 1st of November 2011 and the 3rd of February 2021. Western Ontario and McMaster Universities Arthritis Index (WOMAC) scores, visual analog scale (VAS) scores, International Knee Documentation Committee (IKDC) scores, and adverse events were used as outcomes for evaluation; (3) Results: A total of 14 RCTs were enrolled. At 6 months, revealed that the LR-PRP group was better than the HA group in WOMAC total, pain, and physical function scores. At 12 months, the LR-PRP group was better than the HA group in WOMAC stiffness and physical function scores. There was no significant difference in adverse events; (4) Conclusion: LR-PRP injection showed no significant pain relief effect as compared with HA injection. However, LR-PRP demonstrated better overall outcomes as compared to HA in knee OA patients at the follow-up periods of 3, 6, and 12 months. LR-PRP injection may be recommended as a feasible option in treating patients with knee OA.
机构:
Sorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
Berkani, Sabryne
Courties, Alice
论文数: 0引用数: 0
h-index: 0
机构:
Sorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
Courties, Alice
Eymard, Florent
论文数: 0引用数: 0
h-index: 0
机构:
Henri Mondor Hosp, AP HP, Rheumatol Dept, F-94000 Creteil, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
Eymard, Florent
Latourte, Augustin
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris, Lariboisiere Hosp, AP HP, DMU Locomot,Rheumatol Dept,Inserm U1132, F-75010 Paris, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
Latourte, Augustin
Richette, Pascal
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris, Lariboisiere Hosp, AP HP, DMU Locomot,Rheumatol Dept,Inserm U1132, F-75010 Paris, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
Richette, Pascal
Berenbaum, Francis
论文数: 0引用数: 0
h-index: 0
机构:
Sorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
Berenbaum, Francis
Sellam, Jeremie
论文数: 0引用数: 0
h-index: 0
机构:
Sorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
Sellam, Jeremie
Louati, Karine
论文数: 0引用数: 0
h-index: 0
机构:
Sorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, FranceSorbonne Univ, St Antoine Hosp, AP HP, Rheumatol Dept,Inserm,UMRS 938, F-75012 Paris, France
机构:
Univ Washington, Valley Med Ctr, Valley Family Med Residency, Renton, WA 98055 USAUniv Washington, Valley Med Ctr, Valley Family Med Residency, Renton, WA 98055 USA
Wilcox, Carrie Lynn
Kelsberg, Gary
论文数: 0引用数: 0
h-index: 0
机构:
Univ Washington, Valley Med Ctr, Valley Family Med Residency, Renton, WA 98055 USAUniv Washington, Valley Med Ctr, Valley Family Med Residency, Renton, WA 98055 USA
Kelsberg, Gary
Safranek, Sarah
论文数: 0引用数: 0
h-index: 0
机构:
Univ Washington, Hlth Sci Lib, Seattle, WA 98195 USAUniv Washington, Valley Med Ctr, Valley Family Med Residency, Renton, WA 98055 USA
机构:
Ballarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, AustraliaBallarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
Sibillin, Olivia
Mitchell, David
论文数: 0引用数: 0
h-index: 0
机构:
Ballarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
NOVAR MUSCULOSKELETAL RES INST, Dept Orthopaed, Ballarat, Vic, AustraliaBallarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
Mitchell, David
Harris, Greg
论文数: 0引用数: 0
h-index: 0
机构:
Ballarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, AustraliaBallarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
Harris, Greg
Harvey, Jack
论文数: 0引用数: 0
h-index: 0
机构:
Federation Univ, Sch Sci Psychol & Sport, Ballarat, Vic, Australia
Victoria Univ, Inst Hlth & Sport, Ballarat, Vic, AustraliaBallarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
Harvey, Jack
Spencer, Polly
论文数: 0引用数: 0
h-index: 0
机构:
Gold Coast Univ Hosp, Dept Anaesthet, Southport, Qld, AustraliaBallarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
Spencer, Polly
Spencer, Luke
论文数: 0引用数: 0
h-index: 0
机构:
Ballarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
NOVAR MUSCULOSKELETAL RES INST, Dept Orthopaed, Ballarat, Vic, AustraliaBallarat Orthopaed & Sports Med Clin, Dept Orthopaed, Lake Wendouree, Vic, Australia
机构:
Univ Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, MexicoUniv Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, Mexico
Alvarez Lozano, Eduardo
Gonzalez Paras, Alejandro
论文数: 0引用数: 0
h-index: 0
机构:
Univ Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, MexicoUniv Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, Mexico
Gonzalez Paras, Alejandro
Quintanilla Loredo, Ramon
论文数: 0引用数: 0
h-index: 0
机构:
Univ Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, MexicoUniv Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, Mexico
Quintanilla Loredo, Ramon
Cerda Garcia, Margia Victoria
论文数: 0引用数: 0
h-index: 0
机构:
Univ Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, MexicoUniv Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, Mexico
Cerda Garcia, Margia Victoria
Forriol, Francisco
论文数: 0引用数: 0
h-index: 0
机构:
Univ CEU San Pablo, Sch Med, Campus Monteprincipe, Madrid 28668, SpainUniv Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, Mexico
Forriol, Francisco
Bravo Molina, Beatriz
论文数: 0引用数: 0
h-index: 0
机构:
Univ CEU San Pablo, Sch Med, Campus Monteprincipe, Madrid 28668, SpainUniv Autonoma Nuevo Leon, Hosp Eleuterio Gonzalez, Sch Med, Orthopaed Surg Dept, Monterrey, Mexico
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Natl Def Med Ctr, Integrated Pain Management Ctr, Triserv Gen Hosp, Sch Med, Taipei 11490, Taiwan
Natl Def Med Ctr, Sch Med, Dept Res & Dev, Taipei 11490, TaiwanNatl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Wu, Yung-Tsan
Li, Tsung-Ying
论文数: 0引用数: 0
h-index: 0
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Natl Def Med Ctr, Integrated Pain Management Ctr, Triserv Gen Hosp, Sch Med, Taipei 11490, TaiwanNatl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Li, Tsung-Ying
Lee, Kuei-Chen
论文数: 0引用数: 0
h-index: 0
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Natl Def Med Ctr, Grad Inst Med Sci, Taipei 11490, TaiwanNatl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Lee, Kuei-Chen
Lam, King Hei Stanley
论文数: 0引用数: 0
h-index: 0
机构:
Hong Kong Inst Musculoskeletal Med, Hong Kong, Peoples R China
Chinese Univ Hong Kong, Dept Family Med, Hong Kong, Peoples R China
Univ Hong Kong, Dept Family Med, Hong Kong, Peoples R China
Taipei Med Univ, Wan Fang Hosp, Ctr Reg Anesthesia & Pain Med, Taipei 116, TaiwanNatl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Lam, King Hei Stanley
Chang, Chih-Ya
论文数: 0引用数: 0
h-index: 0
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Natl Yang Ming Chiao Tung Univ, Dept Phys Therapy & Assist Technol, Taipei 112, TaiwanNatl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Chang, Chih-Ya
Chang, Cheng-Kuang
论文数: 0引用数: 0
h-index: 0
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Radiol, Taipei 11490, TaiwanNatl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan
Chang, Cheng-Kuang
Chen, Liang-Cheng
论文数: 0引用数: 0
h-index: 0
机构:
Natl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, TaiwanNatl Def Med Ctr, Triserv Gen Hosp, Sch Med, Dept Phys Med & Rehabil, Taipei 11490, Taiwan