The burden of hospitalizations for meningococcal infection in Spain (1997-2008)

被引：25

作者：

Gil-Prieto, Ruth ^{[1
]}

Garcia-Garcia, Laura ^{[1
]}

Alvaro-Meca, Alejandro ^{[1
]}

Gonzalez-Escalada, Alba ^{[1
]}

Viguera Ester, Pablo ^{[1
]}

Gil De Miguel, Angel ^{[1
]}

机构：

[1] Rey Juan Carlos Univ, Dept Prevent Med & Publ Hlth & Med Immunol & Micr, Madrid 28922, Spain

来源：

VACCINE | 2011年 / 29卷 / 34期

关键词：

Hospitalizations; Meningococcal infection; Spain; DISEASE; EPIDEMIOLOGY; ADMISSIONS;

D O I：

10.1016/j.vaccine.2011.05.089

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

All hospital discharges and deaths related to invasive meningococcal disease, meningococcal meningitis and meningococcemia in the general population from 1997 to 2008 in Spain were obtained. Among the 11,611 meningococcal infection related discharges 53% were meningococcal meningitis and 55% were meningococcemia. The annual hospitalization rate was 2.33, 1.23 and 1.29 cases per 100,000 for invasive meningococcal disease, meningococcal meningitis and meningococcemia, respectively. 846 deaths for invasive meningococcal disease, 235 for meningococcal meningitis and 605 for meningococcemia were reported. Although an important decrease in meningococcal infections related morbidity and mortality has occurred in the last twelve years in Spain, they still continue being major causes of hospitalization and death, especially in the children up to 2 years of age. Future preventive measures, such as vaccination with vaccines covering new conjugated serogroups (B and ACYW135), could further improve population health. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5765 / 5770

页数：6

共 22 条

[1]

BILUKHA R, 200554RR07 NAT CTR I, P1

[2]

CUADRADO AR, 2000, REV FUENTES ESTADIST, V49, P18

[3] Incidence of invasive meningococcal diseases in children in Northern France: Usefulness and limits of the discharge code database for correcting compulsory notification data [J].

Dubos, F. ;

Marechal, I. ;

Tilmont, B. ;

Courouble, C. ;

Leclerc, F. ;

Martinot, A. .

ARCHIVES DE PEDIATRIE, 2009, 16 (07) :984-990

[4] Epidemiology of pneumococcal meningitis hospitalizations in pediatric population in Spain (1998-2006) [J].

Gil Prieto, R. ;

San Roman Montero, J. ;

Gomez Alejandre, C. ;

Alvaro Meca, L. A. ;

Rivero, A. ;

Gil de Miguel, A. .

VACCINE, 2009, 27 (20) :2669-2673

[5] Hospital admissions for meningococcal infections in Madrid, Spain (1997-2005) [J].

Gil Prieto, Ruth ;

Alvarez Moran, Jose Luis ;

Portugal, Pilar ;

San Roman Montero, Jesus ;

Alvaro, Alejandro ;

Rivero Cuadrado, Agustin .

MEDICINA CLINICA, 2010, 134 (12) :534-539

[6]

GRANOFF D, 2003, VACCINES

[7] Global epidemiology of meningococcal disease [J].

Harrison, Lee H. ;

Trotter, Caroline L. ;

Ramsay, Mary E. .

VACCINE, 2009, 27 :B51-B63

[8] Epidemiological Profile of Meningococcal Disease in the United States [J].

Harrison, Lee H. .

CLINICAL INFECTIOUS DISEASES, 2010, 50 :S37-S44

[9]

*I NAC SAL, 2002, CONJ MIN BAS DAT HOS

[10] The epidemiology of meningococcal disease and the impact of vaccines [J].

Khatami, Ameneh ;

Pollard, Andrew J. .

EXPERT REVIEW OF VACCINES, 2010, 9 (03) :285-298

← 1 2 3 →