Chemical Constituents from Scindapsus officinalis (Roxb.) Schott. and Their Anti-Inflammatory Activities

被引：5

作者：

Dong, Hongjing ^{[1
]}

Geng, Yanling ^{[1
]}

Wang, Xueyong ^{[2
]}

Song, Xiangyun ^{[1
]}

Wang, Xiao ^{[1
]}

Yu, Jinqian ^{[1
]}

机构：

[1] Qilu Univ Technol, Shandong Acad Sci, Shandong Anal & Test Ctr, Shandong Key Lab TCM Qual Control Technol, Jinan 250014, Shandong, Peoples R China

[2] Beijing Univ Chinese Med, Coll Chinese Mareria Med, Beijing 100102, Peoples R China

来源：

MOLECULES | 2018年 / 23卷 / 10期

关键词：

Scindapsus officinalis; monoterpene glycoside; phenyl glycoside; caffeoyl derivative; anti-inflammatory activity;

D O I：

10.3390/molecules23102577

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

One new monoterpene glycoside (1), one new phenyl glycoside (2), one new caffeoyl derivative (3), were isolated from Scindapsus officinalis (Roxb.) Schott., along with four known compounds (4-7). Structures of the isolated compounds were elucidated by extensive analysis of spectroscopic data, especially 2D NMR data and comparison with literatures. All isolates were evaluated for anti-inflammatory activity against nitric oxide (NO) production in vitro. Compounds 3 and 7 exhibited moderate inhibitory effects on NO production with IC50 values of 12.2 +/- 0.8 and 18.9 +/- 0.3 mu M, respectively.

引用

页数：10

共 18 条

[1] Study on the chemical constituents of Daphniphyllum angustifolium [J].

Bai, Haiyun ;

Hu, Lihong .

HELVETICA CHIMICA ACTA, 2006, 89 (05) :884-894

[2] Anti-Inflammatory Effects of 6,8-Diprenyl-7,4′-dihydroxyflavanone from Sophora tonkinensis on Lipopolysaccharide-Stimulated RAW 264.7 Cells [J].

Chae, Hee-Sung ;

Yoo, Hunseung ;

Kim, Young-Mi ;

Choi, Young Hee ;

Lee, Chang Hoon ;

Chin, Young-Won .

MOLECULES, 2016, 21 (08)

[3] Chemotaxonomy of Hawaiian Anthurium Cultivars Based on Multivariate Analysis of Phenolic Metabolites [J].

Clark, Benjamin R. ;

Bliss, Barbara J. ;

Suzuki, Jon Y. ;

Borris, Robert P. .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2014, 62 (46) :11323-11334

[4] Isolation and phytotoxicity of apocarotenoids from Chenopodium album [J].

DellaGreca, M ;

Di Marino, C ;

Zarrelli, A ;

D'Abrosca, B .

JOURNAL OF NATURAL PRODUCTS, 2004, 67 (09) :1492-1495

[5] Phenolics from Mikania micrantha and Their Antioxidant Activity [J].

Dong, Li-Mei ;

Jia, Xu-Chao ;

Luo, Qing-Wen ;

Zhang, Qiang ;

Luo, Bi ;

Liu, Wen-Bin ;

Zhang, Xu ;

Xu, Qiao-Lin ;

Tan, Jian-Wen .

MOLECULES, 2017, 22 (07)

[6] A new pyrrole alkaloid isolated from Arum palaestinum Boiss. and its biological activities [J].

El-Desouky, S. K. ;

Kim, Ki Hun ;

Ryu, Shi Young ;

Eweas, Ahmad Farouk ;

Gamal-Eldeen, Amira M. ;

Kim, Young-Kyoon .

ARCHIVES OF PHARMACAL RESEARCH, 2007, 30 (08) :927-931

[7] Piperidine alkaloids from Alocasia macrorrhiza [J].

Huang, Wenjie ;

Yi, Xiaomin ;

Feng, Jianying ;

Wang, Yihai ;

He, Xiangjiu .

PHYTOCHEMISTRY, 2017, 143 :81-86

[8] Simple synthesis of β-D-glycopyranosides using β-glycosidase from almonds [J].

Kurashima, K ;

Fujii, M ;

Ida, Y ;

Akita, H .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2004, 52 (02) :270-275

[9]

Li Dong-dong, 2011, Zhong Yao Cai, V34, P129

[10]

Li Heng, 1996, Acta Botanica Yunnanica, V18, P14

← 1 2 →