Room-temperature swern oxidations by using a microscale flow system

被引：203

作者：

Kawaguchi, T

Miyata, H

Ataka, K

Mae, K

Yoshida, J ^{[1
]}

机构：

[1] Kyoto Univ, Grad Sch Engn, Dept Synth Chem & Biol Chem, Kyoto 6158510, Japan

[2] Kyoto Univ, Microchem Proc Technol Res Assoc MCPT, Kyoto 6158510, Japan

[3] Ube Ind Ltd, Corp Res & Dev, Ube, Yamaguchi 7558633, Japan

[4] Kyoto Univ, Grad Sch Engn, Dept Chem Engn, Kyoto 6158510, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 16期

关键词：

alcohols; microreactors; oxidation; Swern oxidation; synthetic methods;

D O I：

10.1002/anie.200462466

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Equation Presented) Residence time controlled reaction: The Swern oxidation of alcohols has been accomplished by using a microscale flow system, consisting of micromixers and microscale tube reactors (see schematic representation ; DMSO = dimethylsulfoxide, TFAA = trifluoroacetic anhydride), at higher temperatures (-20 to 20°C) than those for conventional macroscale batch systems (-50°C or below). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2413 / 2416

页数：4

共 39 条

[1] Microreactors for elemental fluorine [J].