Human immunodeficiency virus type 1 tropism for T-lymphoid cell lines: Role of the V3 loop and C4 envelope determinants

被引：77
作者：
Carrillo, A
Ratner, L
机构：
[1] WASHINGTON UNIV,SCH MED,DEPT MED,ST LOUIS,MO 63110
[2] WASHINGTON UNIV,SCH MED,DEPT PATHOL,ST LOUIS,MO 63110
[3] WASHINGTON UNIV,SCH MED,DEPT MOLEC MICROBIOL,ST LOUIS,MO 63110
来源：
JOURNAL OF VIROLOGY | 1996年 / 70卷 / 02期
关键词：
D O I：
10.1128/JVI.70.2.1301-1309.1996
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
A functional analysis of chimeric proviral clones generated from the T-cell line-tropic isolate HXB2 and the non-T-cell line-tropic isolate YU-2 identified the minimal determinant for infection of T-lymphoid cell lines to include two interacting domains: the V3 loop and a small region of the C4 domain.
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页码：1301 / 1309
页数：9
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