Fabrication of oligonucleotide chips by using parallel cantilever-based electrochemical deposition in picoliter volumes

被引：34

作者：

Descamps, Emeline

Leichle, Thierry

Corso, Bruno

Laurent, Sebastien

Mailley, Pascal

Nicu, Liviu

Livache, Thierry

Bergaud, Christian

机构：

[1] CEA Grenoble, DRFMC, CNRS, UMR 5819,SPrAM, F-38054 Grenoble 9, France

[2] CNRS, LAAS, Nanobiotechnol Grp, F-31077 Toulouse, France

来源：

ADVANCED MATERIALS | 2007年 / 19卷 / 14期

关键词：

D O I：

10.1002/adma.200602152

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The use of a parallel cantilever-based deposition system as an electrospotting tool in picoliter volumes is demonstrated. Applied in conjunction with polypyrrole electrochemistry, this generic approach for fabricating biochips is optimized for oligonucleotide chips featuring micrometer spots of different sequences with high reproducibility and specificity (see figure).

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页码：1816 / +

页数：7

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