Single-cell profiling lights different cell trajectories in plants

被引：4

作者：

Zheng, Hong-xiang ^{[1
]}

Wu, Feng-hui ^{[1
]}

Li, Si-min ^{[1
]}

Zhang, Xian Sheng ^{[2
]}

Sui, Na ^{[1
]}

机构：

[1] Shandong Normal Univ, Coll Life Sci, Shandong Prov Key Lab Plant Stress, Jinan 250014, Shandong, Peoples R China

[2] Shandong Agr Univ, Coll Life Sci, State Key Lab Crop Biol, Tai An 271018, Shandong, Peoples R China

来源：

ABIOTECH | 2021年 / 2卷 / 01期

关键词：

Epigenomes; Plant development; Plant stem cells; Single-cell multi-omics; Single-cell RNA sequencing; PLURIPOTENT STEM-CELLS; GENE-EXPRESSION; HIGH-THROUGHPUT; RNA; REVEALS; CHROMATIN; METHYLATION; TRIGGERS; DYNAMICS; CORTEX;

D O I：

10.1007/s42994-021-00040-7

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The molecular mechanism of the maintenance and differentiation of plant stem cells is an eternal theme in studies on plant growth and development. Recent advances in single-cell RNA sequencing (scRNA-seq) methods have completely changed the understanding of cell heterogeneity and cell function, allowing research precision to identify the differentiation trajectory of stem cells maintained and differentiated at the cellular level. This review aimed to mainly discuss the novel insights provided by scRNA-seq for the maintenance and initiation of plant stem cells, cell differentiation, cell response to environmental changes, and improvement strategies for scRNA-seq. In addition, it highlighted additional perspectives beyond scRNA-seq, such as spatial transcriptomes, epigenomes, and single-cell multiomics, for a renewed understanding of stem cell maintenance and cell differentiation, thus providing potential targets and theoretical foundations for crop improvement.

引用

页码：64 / 78

页数：15

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