Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis

被引：96
作者：
Morikawa, T [1 ]
Kishi, A [1 ]
Pongpiriyadacha, Y [1 ]
Matsuda, H [1 ]
Yoshikawa, M [1 ]
机构：
[1] Kyoto Pharmaceut Univ, Yamashina Ku, Kyoto 6078412, Japan
来源：
JOURNAL OF NATURAL PRODUCTS | 2003年 / 66卷 / 09期
关键词：
D O I：
10.1021/np0301543
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Three new friedelane-type triterpenes named salasones A (1), B (2), and C (3), a new norfriedelane-type triterpene, salaquinone A (4), and a new acylated eudesmane-type sesquiterpene, salasol A (5), were isolated from the 80% aqueous methanolic extract of the stems of Salacia chinensis collected in Thailand. Their stereostructures were elucidated on the basis of chemical and physicochemical evidence. In addition, six constituents, 3beta,22beta-dihydroxyolean-12-en-29-oic acid, tingenone, tingenine B, regeol A, triptocalline A, and mangiferin, were found to show an inhibitory effect on rat lens aldose reductase.
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收藏
页码：1191 / 1196
页数：6
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