Embryotoxicity and Biotransformation Responses in Zebrafish Exposed to Water-Soluble Fraction of Crude Oil

被引:14
作者
Pauka, Luciana M. [1 ]
Maceno, Marcell [1 ]
Rossi, Stefani C. [1 ]
Silva de Assis, Helena C. [1 ]
机构
[1] Univ Fed Parana, Dept Pharmacol, BR-81531990 Curitiba, Parana, Brazil
关键词
Danio rerio; Zebrafish; Crude oil; Embryotoxicity; Biotransformation; POLYCYCLIC AROMATIC-HYDROCARBONS; FISH; TOXICITY; ETHANOL;
D O I
10.1007/s00128-011-0235-x
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The toxic effects of water-soluble fraction (WSF) of crude oil (API27, Petrobras Campos Basin, Brazil) were evaluated during the early life stages of zebrafish, as well as its biotransformation in juvenile fish. Embryonic development was studied during 96 h. Reduced heartbeat rate, weak pigmentation, tail defects, and embryo mortality were observed for all of the tested concentrations of the WSF. Activities of the biotransformation enzymes were induced at the highest concentrations, showing that these enzymes played a role in its elimination. As shown in this study the crude oil WSF altered the normal embryonic development of fish.
引用
收藏
页码:389 / 393
页数:5
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