Sex, sex chromosomes and gene expression

被引：3

作者：

Lu, Xuemei ^{[2
]}

Wu, Chung-I ^{[1
,2
]}

机构：

[1] Univ Chicago, Dept Ecol & Evolut, Chicago, IL 60637 USA

[2] Chinese Acad Sci, Beijing Inst Genom, Lab Dis Genom & Individualized Med, Beijing, Peoples R China

来源：

BMC BIOLOGY | 2011年 / 9卷

关键词：

X-CHROMOSOME; EVOLUTION;

D O I：

10.1186/1741-7007-9-30

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The X chromosome has fewer testis-specific genes than autosomes in many species. This bias is commonly attributed to X inactivation in spermatogenesis but a recent paper in BMC Biology provides evidence against X inactivation in Drosophila and proposes that somatic tissue- and testis- but not ovary-specific genes tend not to be located on the X chromosome. Here, we discuss possible mechanisms underlying this bias, including sexual antagonism and dosage compensation.

引用

页数：3

共 11 条

[1] Extensive gene traffic on the mammalian X chromosome [J].

Emerson, JJ ;

Kaessmann, H ;

Betrán, E ;

Long, MY .

SCIENCE, 2004, 303 (5657) :537-540

[2] X-chromosome inactivation: a hypothesis linking ontogeny and phylogeny [J].

Huynh, KD ;

Lee, JT .

NATURE REVIEWS GENETICS, 2005, 6 (05) :410-418

[3] Genome-wide misexpression of X-linked versus autosomal genes associated with hybrid male sterility [J].

Lu, Xuemei ;

Shapiro, Joshua A. ;

Ting, Chau-Ti ;

Li, Yan ;

Li, Chunyan ;

Xu, Jin ;

Huang, Huanwei ;

Cheng, Ya-Jen ;

Greenberg, Anthony J. ;

Li, Shou-Hsien ;

Wu, Mao-Lien ;

Shen, Yang ;

Wu, Chung-I .

GENOME RESEARCH, 2010, 20 (08) :1097-1102

[4] SEX-CHROMOSOMES, RECOMBINATION, AND CHROMATIN CONFORMATION [J].

MCKEE, BD ;

HANDEL, MA .

CHROMOSOMA, 1993, 102 (02) :71-80

[5] Lack of global meiotic sex chromosome inactivation, and paucity of tissue-specific gene expression on the Drosophila X chromosome [J].

Mikhaylova, Lyudmila M. ;

Nurminsky, Dmitry I. .

BMC BIOLOGY, 2011, 9

[6] Paucity of genes on the Drosophila X chromosome showing male-biased expression [J].

Parisi, M ;

Nuttall, R ;

Naiman, D ;

Bouffard, G ;

Malley, J ;

Andrews, J ;

Eastman, S ;

Oliver, B .

SCIENCE, 2003, 299 (5607) :697-700

[7]

RICE WR, 1984, EVOLUTION, V38, P735, DOI 10.1111/j.1558-5646.1984.tb00346.x

[8] Demasculinization of X chromosomes in the Drosophila genus [J].

Sturgill, David ;

Zhang, Yu ;

Parisi, Michael ;

Oliver, Brian .

NATURE, 2007, 450 (7167) :238-U3

[9] Evolution on the X chromosome: unusual patterns and processes [J].

Vicoso, Beatriz ;

Charlesworth, Brian .

NATURE REVIEWS GENETICS, 2006, 7 (08) :645-653

[10] Sexual antagonism and X inactivation - the SAXI hypothesis [J].

Wu, CI ;

Xu, EY .

TRENDS IN GENETICS, 2003, 19 (05) :243-247

← 1 2 →