Three new triterpene saponins from Actinostemma lobatum MAXIM and their cytotoxicity in vitro

被引：7

作者：

Cao, Jia-qing ^{[1
]}

Li, Wei ^{[1
,2
]}

Tang, Yun ^{[2
]}

Zhang, Xiang-rong ^{[1
]}

Li, Wei ^{[1
,2
]}

Zhao, Yu-qing ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Med, Shenyang 110016, Peoples R China

[2] Yichun Univ, Key Lab Nat Act Pharmaceut Constituents Jiangx Pr, Yichun 336000, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2015年 / 11卷

基金：

美国国家科学基金会;

关键词：

Actinostemma lobatum; Triterpene saponin; Cytotoxicity; CYCLIC BISDESMOSIDES; LOBATOSIDE-C; CONSTITUENTS; GLYCOSIDES; HERB; ACID;

D O I：

10.1016/j.phytol.2015.01.016

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new triterpene saponins, lobatoside O (1), actinostemmoside I (2) and actinostemmoside J (3), were isolated from the herb of Actinostemma lobatum MAXIM. Their structures were elucidated by means of extensive chemical and spectroscopic methods. In addition, cytotoxic activities toward HCT-116, HT-29, MCF-7 and A549 cell lines were tested by the MTT method. (C) 2015 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

引用

页码：301 / 305

页数：5

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