Isolates of the emerging pathogen Candida auris present in the UK have several geographic origins

被引:104
作者
Borman, Andrew M. [1 ]
Szekely, Adrien [1 ]
Johnson, Elizabeth M. [1 ]
机构
[1] Publ Hlth England South West, UK Natl Mycol Reference Lab MRL, Bristol, Avon, England
关键词
pathogenic yeasts; Candida auris; emerging pathogen; rDNA sequencing; clonal strains; United Kingdom; ANTIFUNGAL SUSCEPTIBILITY; AMPHOTERICIN-B; CLONAL STRAIN; SP NOV;
D O I
10.1093/mmy/myw147
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Candida auris has recently emerged as a serious nosocomial health risk, with widespread outbreaks in numerous hospitals worldwide and the existence of geographic region-specific discrete clonal lineages. Here we have compared the rDNA sequences of 24 isolates of Candida auris from 14 different hospital centers in the United Kingdom with those of strains from different international origins present in the public sequence databases. Here we show that UK isolates of C. auris fall into three well-supported clades corresponding to lineages that have previously been reported from India, Malaysia and Kuwait, Japan and Korea, and South Africa, respectively.
引用
收藏
页码:563 / 567
页数:5
相关论文
共 23 条
[1]   Comparative Pathogenicity of United Kingdom Isolates of the Emerging Pathogen Candida auris and Other Key Pathogenic Candida Species [J].
Borman, Andrew M. ;
Szekely, Adrien ;
Johnson, Elizabeth M. .
MSPHERE, 2016, 1 (04)
[2]   Novel Taxa Associated with Human Fungal Black-Grain Mycetomas: Emarellia grisea gen. nov., sp nov., and Emarellia paragrisea sp nov. [J].
Borman, Andrew M. ;
Desnos-Ollivier, Marie ;
Campbell, Colin K. ;
Bridge, Paul D. ;
Dannaoui, Eric ;
Johnson, Elizabeth M. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2016, 54 (07) :1738-1745
[3]   Epidemiology, Antifungal Susceptibility, and Pathogenicity of Candida africana Isolates from the United Kingdom [J].
Borman, Andrew M. ;
Szekely, Adrien ;
Linton, Chistopher J. ;
Palmer, Michael D. ;
Brown, Phillipa ;
Johnson, Elizabeth M. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2013, 51 (03) :967-972
[4]   First report of Candida auris in America: Clinical and microbiological aspects of 18 episodes of candidemia [J].
Calvo, Belinda ;
Melo, Analy S. A. ;
Perozo-Mena, Armindo ;
Hernandez, Martin ;
Francisco, Elaine Cristina ;
Hagen, Ferry ;
Meis, Jacques F. ;
Colombo, Arnaldo Lopes .
JOURNAL OF INFECTION, 2016, 73 (04) :369-374
[5]   Multidrug-resistant endemic clonal strain of Candida auris in India [J].
Chowdhary, A. ;
Kumar, V. Anil ;
Sharma, C. ;
Prakash, A. ;
Agarwal, K. ;
Babu, R. ;
Dinesh, K. R. ;
Karim, S. ;
Singh, S. K. ;
Hagen, F. ;
Meis, J. F. .
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2014, 33 (06) :919-926
[6]   New Clonal Strain of Candida auris, Delhi, India [J].
Chowdhary, Anuradha ;
Sharma, Cheshta ;
Duggal, Shalini ;
Agarwal, Kshitij ;
Prakash, Anupam ;
Singh, Pradeep Kumar ;
Jain, Sarika ;
Kathuria, Shallu ;
Randhawa, Harbans S. ;
Hagen, Ferry ;
Meis, Jacques F. .
EMERGING INFECTIOUS DISEASES, 2013, 19 (10) :1670-1673
[7]   Rapid identification of 6328 isolates of pathogenic yeasts using MALDI-ToF MS and a simplified, rapid extraction procedure that is compatible with the Bruker Biotyper platform and database [J].
Fraser, Mark ;
Brown, Zoe ;
Houldsworth, Marian ;
Borman, Andrew M. ;
Johnson, Elizabeth M. .
MEDICAL MYCOLOGY, 2016, 54 (01) :80-88
[8]   Multidrug-Resistant Candida auris Misidentified as Candida haemulonii: Characterization by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and DNA Sequencing and Its Antifungal Susceptibility Profile Variability by Vitek 2, CLSI Broth Microdilution, and Etest Method [J].
Kathuria, Shallu ;
Singh, Pradeep K. ;
Sharma, Cheshta ;
Prakash, Anupam ;
Masih, Aradhana ;
Kumar, Anil ;
Meis, Jacques F. ;
Chowdhary, Anuradha .
JOURNAL OF CLINICAL MICROBIOLOGY, 2015, 53 (06) :1823-1830
[9]   MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability [J].
Katoh, Kazutaka ;
Standley, Daron M. .
MOLECULAR BIOLOGY AND EVOLUTION, 2013, 30 (04) :772-780
[10]   Candida haemulonii and Closely Related Species at 5 University Hospitals in Korea: Identification, Antifungal Susceptibility, and Clinical Features [J].
Kim, Mi-Na ;
Shin, Jong Hee ;
Sung, Heungsup ;
Lee, Kyungwon ;
Kim, Eui-Chong ;
Ryoo, Namhee ;
Lee, Jin-Sol ;
Jung, Sook-In ;
Park, Kyung Hwa ;
Kee, Seung Jung ;
Kim, Soo Hyun ;
Shin, Myung Geun ;
Suh, Soon Pal ;
Ryang, Dong Wook .
CLINICAL INFECTIOUS DISEASES, 2009, 48 (06) :e57-e61