New alkaloid-like heterocycles via formal aza-[3+2] cycloaddition reaction of cyclic enaminones with cyclopropenones

被引：32

作者：

Cunha, Silvio ^{[1
]}

Damasceno, Fabiano ^{[1
]}

Ferrari, Jailton ^{[1
]}

机构：

[1] Univ Fed Bahia, Inst Quim, BR-417090 Salvador, BA, Brazil

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 33期

关键词：

enaminone; pyrrolizidine; indolizidine;

D O I：

10.1016/j.tetlet.2007.06.087

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The formal aza-[3+2] cycloaddition reactions of cyclopropen ones and cyclic enaminones, including a chiral one, were employed for the first time in the direct formation of new pyrrolidine and indolizidine derivatives. The regiochemistry of cyclization is dependent of both ring size and steric factors of enaminones. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：5795 / 5798

页数：4

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