Cell Modelling of Hematopoiesis

被引：14
作者：
Bessonov, N. [2 ]
Pujo-Menjouet, L. [1 ]
Volpert, V. [1 ]
机构：
[1] Univ Lyon 1, Inst Camille Jordan, CNRS UMR 5208, F-69200 Villeurbanne, France
[2] Inst Mech Engn Problems, St Petersburg 199178, Russia
来源：
MATHEMATICAL MODELLING OF NATURAL PHENOMENA | 2006年 / 1卷 / 02期
关键词：
hematopoiesis modelling; multi-agent; leukemia; stem cell; bone marrow; cell competition;
D O I：
10.1051/mmnp:2008005
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
In this work, we introduce a new software created to study hematopoiesis at the cell population level with the individually based approach. It can be used as an interface between theoretical works on population dynamics and experimental observations. We show that this software can be useful to study some features of normal hematopoiesis as well as some blood diseases such as myelogenous leukemia. It is also possible to simulate cell communication and the formation of cell colonies in the bone marrow.
引用
收藏
页码：81 / 103
页数：23
相关论文
共 27 条
  • [1] A mathematical study of the hematopoiesis process with applications to chronic myelogenous leukemia
    Adimy, M
    Crauste, F
    Ruan, SG
    [J]. SIAM JOURNAL ON APPLIED MATHEMATICS, 2005, 65 (04) : 1328 - 1352
  • [2] Adimy M, 2003, DISCRETE CONT DYN-B, V3, P439
  • [3] A singular transport model describing cellular division
    Adimy, M
    Pujo-Menjouet, L
    [J]. COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE I-MATHEMATIQUE, 2001, 332 (12): : 1071 - 1076
  • [4] Periodic oscillations in leukopoiesis models with two delays
    Adimy, Mostafa
    Crauste, Fabien
    Ruan, Shigui
    [J]. JOURNAL OF THEORETICAL BIOLOGY, 2006, 242 (02) : 288 - 299
  • [5] [Anonymous], KINETICS CELLULAR PR
  • [6] Analysis of cell kinetics using a cell division marker: Mathematical modeling of experimental data
    Bernard, S
    Pujo-Menjouet, L
    Mackey, MC
    [J]. BIOPHYSICAL JOURNAL, 2003, 84 (05) : 3414 - 3424
  • [7] Bifurcations in a white-blood-cell production model
    Bernard, S
    Bélair, J
    Mackey, MC
    [J]. COMPTES RENDUS BIOLOGIES, 2004, 327 (03) : 201 - 210
  • [8] Oscillations in cyclical neutropenia:: new evidence based on mathematical modeling
    Bernard, S
    Bélair, J
    Mackey, MC
    [J]. JOURNAL OF THEORETICAL BIOLOGY, 2003, 223 (03) : 283 - 298
  • [9] BESSONOV N, 2005, P ANN S MATH APPL BI, V2, P79
  • [10] ON EXISTENCE OF A G0-PHASE IN CELL CYCLE
    BURNS, FJ
    TANNOCK, IF
    [J]. CELL AND TISSUE KINETICS, 1970, 3 (04): : 321 - &
123