One-Pot Synthesis of Pyrrolo[3,2-f]- and Pyrrolo[2,3-h]quinoline Derivatives: Observation of an Unexpected Mechanistic Pathway

被引：4

作者：

Ramesh, Subburethinam ^{[1
]}

Nagarajan, Rajagopal ^{[1
]}

机构：

[1] Univ Hyderabad, Sch Chem, Hyderabad 500046, Andhra Pradesh, India

来源：

SYNLETT | 2012年 / 05期

关键词：

pyrroloquinoline; one-pot synthesis; 5-aminoindole; Lewis acid; RED PYRROLOQUINOLINE ALKALOIDS; BUILDING-BLOCKS; CONSTRUCTION; QUINOLINE; EFFICIENT; ACID;

D O I：

10.1055/s-0031-1290565

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

One-pot synthesis of pyrrolo[3,2-f]- and pyrrolo[2,3-h]quinolines were obtained starting from substituted 5-aminoindoles, benzaldehydes, and phenylacetylenes in the presence of La(OTf)(3) as a catalyst in good yields. The indole moiety in 5-aminoindole is believed to be mainly responsible for the observation of unexpected mechanistic pathway to the formation of pyrrolo[2,3-h]quinoline.

引用

页码：717 / 722

页数：6

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