SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER): study protocol for a cluster randomised controlled trial

被引：24

作者：

Sluggett, Janet K. ^{[1
,2
]}

Chen, Esa Y. H. ^{[1
,2
]}

Ilomaki, Jenni ^{[1
,3
]}

Corlis, Megan ^{[2
,4
]}

Hilmer, Sarah N. ^{[2
,5
]}

Van Emden, Jan ^{[2
,4
]}

Ooi, Choon Ean ^{[1
,2
]}

Kim-Huong Nguyen ^{[2
,6
]}

Comans, Tracy ^{[2
,6
,7
]}

Hogan, Michelle ^{[2
,4
]}

Caporale, Tessa ^{[4
]}

Edwards, Susan ^{[8
]}

Quirke, Lyntara ^{[9
]}

Patching, Allan ^{[10
]}

Bell, J. Simon ^{[1
,2
,3
,11
]}

机构：

[1] Monash Univ, Ctr Med Use & Safety, Fac Pharm & Pharmaceut Sci, 381 Royal Parade, Parkville, Vic 3052, Australia

[2] Hornsby Ku Ring Gai Hosp, NHMRC Cognit Decline Partnership Ctr, Hornsby, NSW, Australia

[3] Monash Univ, Dept Epidemiol & Prevent Med, Melbourne, Vic, Australia

[4] Helping Hand Aged Care, Adelaide, SA, Australia

[5] Univ Sydney, Sch Med, Kolling Inst Med Res, Northern Clin Sch,Royal North Shore Hosp, Sydney, NSW, Australia

[6] Griffith Univ, Menzies Hlth Inst Queensland, Meadowbrook, Qld, Australia

[7] Univ Queensland, Ctr Hlth, Serv Res, Woolloogabba, Qld, Australia

[8] Repatriat Gen Hosp, Drug Therapeut Informat Serv, Daw Pk, SA, Australia

[9] Alzheimers Australia, Consumer Representat, Scullin, Australian Capi, Australia

[10] Helping Hand Aged Care, Helping Hand Consumer & Carer Reference Grp, Adelaide, SA, Australia

[11] Univ South Australia, Sch Pharm & Med Sci, Sansom Inst, Adelaide, SA, Australia

来源：

TRIALS | 2018年 / 19卷

基金：

澳大利亚国家健康与医学研究理事会;

关键词：

Medication regimen simplification; Residential aged care; Nursing Homes; Long-term care; Pharmacist; Medication administration; Randomised controlled trial; QUALITY-OF-LIFE; REGIMEN COMPLEXITY; AGED CARE; OLDER-PEOPLE; VALIDATION; ADJUSTMENT; DEMENTIA; HEALTH; ADULTS; INDEX;

D O I：

10.1186/s13063-017-2417-2

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Background: Complex medication regimens are highly prevalent in residential aged care facilities (RACFs). Strategies to reduce unnecessary complexity may be valuable because complex medication regimens can be burdensome for residents and are costly in terms of nursing time. The aim of this study is to investigate application of a structured process to simplify medication administration in RACFs. Methods: SImplification of Medications Prescribed to Long-tErm care Residents (SIMPLER) is a non-blinded, matched pair, cluster randomised controlled trial of a single multidisciplinary intervention to simplify medication regimens. Trained study nurses will recruit English-speaking, permanent residents from eight South Australian RACFs. Medications taken by residents in the intervention arm will be assessed once using a structured tool (the Medication Regimen Simplification Guide for Residential Aged CarE) to identify opportunities to reduce medication regimen complexity (e.g. by administering medications at the same time, or through the use of longer-acting or combination formulations). Residents in the comparison group will receive routine care. Participants will be followed for up to 36 months after study entry. The primary outcome measure will be the total number of charted medication administration times at 4 months after study entry. Secondary outcome measures will include time spent administering medications, medication incidents, resident satisfaction, quality of life, falls, hospitalisation and mortality. Individual-level analyses that account for clustering will be undertaken to determine the impact of the intervention on the study outcomes. Discussion: Ethical approval has been obtained from the Monash University Human Research Ethics Committee and the aged care provider organisation. Research findings will be disseminated through conference presentations and peer-reviewed publications. SIMPLER will enable an improved understanding of the burden of medication use in RACFs and quantify the impact of regimen simplification on a range of outcomes important to residents and care providers.

引用

页数：9

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