The effect of NaCl and Na2SO4 concentration in aqueous phase on the phase inversion temperature O/W nanoemulsions

被引：15

作者：

Sharif, Amir A. Mehrdad ^{[1
]}

Astaraki, Ali M. ^{[1
]}

Azar, Parviz Aberoomand ^{[2
]}

Khorrami, Saeed Abedini ^{[1
]}

Moradi, Shahram ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Appl Chem, Fac Chem, N Tehran Branch, Tehran, Iran

[2] Islamic Azad Univ, Dept Analyt Chem, Sci & Res Branch, Tehran, Iran

来源：

ARABIAN JOURNAL OF CHEMISTRY | 2012年 / 5卷 / 01期

关键词：

Nanoemulsion; Phase inversion temperature (PIT); Emulsion formation; NANO-EMULSIONS; STABILITY; DESIGN; WATER;

D O I：

10.1016/j.arabjc.2010.07.021

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The effect of NaCl and Na2SO4 concentrations in aqueous phase on the phase inversion temperature (PIT) in nanoemulsions of water/Brij30/n-hexadecane system has been studied separately, and then compared. The variation of conductivity with temperature was measured by Cyber Scan PC510 conductivity meter for emulsions with 20 wt% hexadecane and 8 wt% Brij30 concentration and different concentrations of NaCl and Na2SO4 in aqueous phase. The results showed that with increasing concentrations of NaCl and Na2SO4 in aqueous phase, the PIT of nanoemulsions decreases. The effect of the elevation of concentration on the decrease of PIT was more for Na2SO4 in aqueous phase than NaCl with equal concentrations. (C) 2010 King Saud University. Production and hosting by Elsevier B.V. All rights reserved.

引用

页码：41 / 44

页数：4

共 12 条

[1] Baboota Sanjula, 2007, Acta Pharmaceutica (Zagreb), V57, P315, DOI 10.2478/v10007-007-0025-5
[2] Binks B.P., 1998, MODERN ASPECTS EMULS, P395
[3] Design and evaluation of self-nanoemulsifying drug delivery systems (SNEDDS) for cefpodoxime proxetil
Date, Abhijit A.
Nagarsenker, M. S.
[J]. INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2007, 329 (1-2) : 166 - 172
[4] Formation of nano-emulsions by low-energy emulsification methods at constant temperature
Forgiarini, A
Esquena, J
González, C
Solans, C
[J]. LANGMUIR, 2001, 17 (07) : 2076 - 2083
[5] Formation and stability of nano-emulsions prepared using the phase inversion temperature method
Izquierdo, P
Esquena, J
Tadros, TF
Dederen, C
Garcia, MJ
Azemar, N
Solans, C
[J]. LANGMUIR, 2002, 18 (01) : 26 - 30
[6] Studies on the formation of O/W nano-emulsions, by low-energy emulsification methods, suitable for pharmaceutical applications
Sadurní, N
Solans, C
Azemar, N
García-Celma, MJ
[J]. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2005, 26 (05) : 438 - 445
[7] EFFECT OF ADDED SALTS IN WATER ON HYDROPHILE LIPOPHILE BALANCE OF NONIONIC SURFACTANTS - EFFECT OF ADDED SALTS ON PHASE INVERSION TEMPERATURE OF EMULSIONS
SHINODA, K
TAKEDA, H
[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1970, 32 (04) : 642 - &
[8] EFFECT OF TEMPERATURE ON PHASE EQUILIBRIA AND TYPES OF DISPERSIONS OF TERNARY SYSTEM COMPOSED OF WATER CYCLOHEXANE AND NONIONIC SURFACTANT
SHINODA, K
SAITO, H
[J]. JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1968, 26 (01) : 70 - &
[9] Shinoda K., 1983, ENCY EMULSION TECHNO, V1, P337
[10] SOLANS C, 2002, SURFACTANT SCI SERIE

← 1 2 →