Diblock Copolymer Formation via Self-Assembly of Cyclodextrin and Adamantyl End-Functionalized Polymers

被引：56

作者：

Stadermann, Jan ^{[1
]}

Komber, Hartmut ^{[1
]}

Erber, Michael ^{[1
]}

Daebritz, Frank ^{[1
]}

Ritter, Helmut ^{[2
]}

Voit, Brigitte ^{[1
]}

机构：

[1] Leibniz Inst Polymerforsch Dresden eV, D-01069 Dresden, Germany

[2] Univ Dusseldorf, Inst Organ Chem & Makromol Chem, Lehrstuhl Paparat Polymerchem, D-40225 Dusseldorf, Germany

来源：

MACROMOLECULES | 2011年 / 44卷 / 09期

关键词：

BETA-CYCLODEXTRIN; N-ISOPROPYLACRYLAMIDE; CHEMISTRY SYNTHESIS; GRAFT-COPOLYMERS; BLOCK; DRUG; COMPLEXES; HYDROGELS; MICELLES; BEHAVIOR;

D O I：

10.1021/ma200048a

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Two water-soluble polymers poly(2-methyl-2-oxazoline) and poly(N-isopropylacrylamide) with complexing moieties (beta-CD and adamantane, respectively) located at the chain ends were prepared via controlled techniques. To verify the interaction of the beta-CD- and adamantane-type polymer end groups in aqueous solution, detailed complexation studies were carried out by H-1 NMR spectroscopy. It could be proved, that the polymers undergo self-assembly to form the corresponding supramolecular diblock structure. Furthermore, the double-hydrophilic block assembly was observed to be switchable to a hydrophilic-hydrophobic configuration by adjusting temperature leading to reversible aggregate formation.

引用

页码：3250 / 3259

页数：10

共 45 条

[1] New Thermo-Sensitive Graft Copolymers Based on a Poly(N-isopropylacrylamide) Backbone and Functional Polyoxazoline Grafts with Random and Diblock Structure [J].

Carlos Rueda, Juan ;

Zschoche, Stefan ;

Komber, Hartmut ;

Krahl, Franziska ;

Arndt, Karl-Friedrich ;

Voit, Brigitte .

MACROMOLECULAR CHEMISTRY AND PHYSICS, 2010, 211 (06) :706-716

[2] Hydrogels of β-cyclodextrin crosslinked by acylated poly(ethylene glycol): Synthesis and properties [J].

Cesteros, Luis C. ;

Gonzalez-Teresa, R. ;

Katime, Issa .

EUROPEAN POLYMER JOURNAL, 2009, 45 (03) :674-679

[3] Fabrication of thermosensitive PCL-PNIPAAm-PCL triblock copolymeric micelles for drug delivery [J].

Chang, Cong ;

Wei, Hua ;

Quan, Chang-Yun ;

Li, Yong-Yong ;

Liu, Jia ;

Wang, Zong-Chun ;

Cheng, Si-Xue ;

Zhang, Xian-Zheng ;

Zhuo, Ren-Xi .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2008, 46 (09) :3048-3057

[4] Novel hyaluronic acid based supramolecular assemblies stabilized by multivalent specific interactions: Rheological behavior in aqueous solution [J].

Charlot, Aurelia ;

Auzely-Velty, Rachel .

MACROMOLECULES, 2007, 40 (26) :9555-9563

[5] Thermosensitive and Switchable Terpyridine-Functionalized Metallo-Supramolecular Poly(N-isopropylacrylamide) [J].

Chiper, Manuela ;

Fournier, David ;

Hoogenboom, Richard ;

Schubert, Ulrich S. .

MACROMOLECULAR RAPID COMMUNICATIONS, 2008, 29 (20) :1640-1647

[6] Supramolecular self-assembled Ni(II), Fe(II), and Co(II) ABA triblock copolymers [J].

Chiper, Manuela ;

Meier, Michael A. R. ;

Wouters, Daan ;

Hoeppener, Stephanie ;

Fustin, Charles-Andre ;

Gohy, Jean-Francois ;

Schubert, Ulrich S. .

MACROMOLECULES, 2008, 41 (08) :2771-2777

[7] Monoacrylated cyclodextrin via "click" reaction and copolymerization with N-isopropylacrylamide: guest controlled solution properties [J].

Choi, SooWhan ;

Munteanu, Maricica ;

Ritter, Helmut .

JOURNAL OF POLYMER RESEARCH, 2009, 16 (04) :389-394

[8] Diffusion NMR spectroscopy in supramolecular and combinatorial chemistry: An old parameter - New insights [J].

Cohen, Y ;

Avram, L ;

Frish, L .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (04) :520-554

[9] Self-healing and thermoreversible rubber from supramolecular assembly [J].

Cordier, Philippe ;

Tournilhac, Francois ;

Soulie-Ziakovic, Corinne ;

Leibler, Ludwik .

NATURE, 2008, 451 (7181) :977-980

[10] Poly(N-isopropylacrylamide)/poly[(N-acetylimino)ethylene] thermosensitive block and graft copolymers [J].

David, G ;

Alupei, V ;

Simionescu, BC ;

Dinçer, S ;

Piskin, E .

EUROPEAN POLYMER JOURNAL, 2003, 39 (06) :1209-1213

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