Targeted therapies and thyroid cancer: an update

被引：5
|
作者：
de la Fouchardiere, Christelle [1 ]
Droz, Jean-Pierre [1 ]
机构：
[1] Univ Lyon 1, Ctr Leon Berard, F-69008 Lyon, France
来源：
ANTI-CANCER DRUGS | 2011年 / 22卷 / 07期
关键词：
anaplastic thyroid carcinoma; differentiated thyroid carcinoma; medullary thyroid carcinoma; targeted therapy; PHASE-II TRIAL; TYROSINE KINASE INHIBITORS; ADVANCED MEDULLARY; ALTERNATING COMBINATION; PROGNOSTIC-FACTORS; CARCINOMA; SORAFENIB; SUNITINIB; EFFICACY; GROWTH;
D O I：
10.1097/CAD.0b013e32834319c7
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The treatment of metastatic, progressive thyroid cancer has evolved over recent years. New 'targeted' therapeutic approaches have been developed along with advances in the knowledge of thyroid carcinogenesis and the identification of tumor and endothelial targets. In recent years, results of targeted therapies have shown some benefit in refractory, progressive, differentiated, and medullary thyroid carcinomas but not, until recently, in undifferentiated thyroid carcinoma. We review here the different targeted therapies tested in thyroid cancers. Anti-Cancer Drugs 22: 688-699 (C) 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.
引用
收藏
页码：688 / 699
页数：12
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