Recent advances in the application of transmission Raman spectroscopy to pharmaceutical analysis

被引：107
作者：
Buckley, Kevin [1 ,2 ]
Matousek, Pavel [1 ,2 ,3 ]
机构：
[1] Rutherford Appleton Lab, Cent Laser Facil, Sci & Technol Facil Council, Didcot OX11 0QX, Oxon, England
[2] Univ Coll London, Royal Natl Orthopaed Hosp, Inst Orthopaed & Musculoskeletal Sci, Stanmore HA7 4LP, Middx, England
[3] Cobalt Light Syst Ltd, Didcot OX11 0QR, Oxon, England
来源：
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS | 2011年 / 55卷 / 04期
基金：
英国工程与自然科学研究理事会;
关键词：
Transmission Raman; Quantitative analysis; Pharmaceutical formulations; Quality control; TURBID MEDIA; SIGNAL ENHANCEMENT; SPATIAL-RESOLUTION; ACTIVE INGREDIENT; PHOTON MIGRATION; FLUORESCENCE; SCATTERING; TABLETS; CAPSULES; STANDARDIZATION;
D O I：
10.1016/j.jpba.2010.10.029
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
This article reviews recent advances in transmission Raman spectroscopy and its applications, from the perspective of pharmaceutical analysis. The emerging concepts enable rapid non-invasive volumetric analysis of pharmaceutical formulations and could lead to many important applications in pharmaceutical settings, including quantitative bulk analysis of intact pharmaceutical tablets and capsules in quality and process control. Crown Copyright (C) 2010 Published by Elsevier B.V. All rights reserved.
引用
收藏
页码：645 / 652
页数：8
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