Interplay of parasite-driven immune responses and autoimmunity

被引：50
作者：
Zaccone, Paola [1 ]
Burton, Oliver T. [1 ]
Cooke, Anne [1 ]
机构：
[1] Dept Pathol, Cambridge CB2 1QP, England
来源：
TRENDS IN PARASITOLOGY | 2008年 / 24卷 / 01期
基金：
英国生物技术与生命科学研究理事会; 英国惠康基金;
关键词：
D O I：
10.1016/j.pt.2007.10.006
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
As more facts emerge regarding the ways in which parasite-derived molecules modulate the host immune response, it is possible to envisage how a lack of infection by agents that once infected humans commonly might contribute to the rise in autoimmune disease. Through effects on cells of both the innate and adaptive arms of the immune response, parasites can orchestrate a range of outcomes that are beneficial not only to parasites, in terms of facilitating their life cycles, but also to their host, in limiting pathology.
引用
收藏
页码：35 / 42
页数：8
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