Expression of the DNA-binding factor TOX promotes the encephalitogenic potential of microbe-induced autoreactive CD8+T cells

被引:0
|
作者
Nicolas, Page [1 ]
Bogna, Klimek [1 ]
Mathias, De Roo [2 ,3 ]
Karin, Steinbach [1 ]
Hadrien, Soldati [4 ]
Sylvain, Lemeille [1 ]
Ingrid, Wagner [1 ]
Mario, Kreutzfeldt [1 ]
Giovanni, Di Liberto [1 ]
Ilena, Vincenti [1 ]
Thomas, Lingner [5 ]
Gabriela, Salinas [5 ]
Wolfgang, Brueck [6 ]
Mikael, Simons [7 ,8 ,9 ]
Rabih, Murr [4 ]
Jonathan, Kaye [10 ,11 ]
Dietmar, Zehn [12 ]
Daniel, Pinschewer D. [13 ]
Doron, Merkler [1 ,14 ]
机构
[1] Univ Geneva, Dept Pathol & Immunol, Geneva, Switzerland
[2] Geneva Univ Hosp, Dept Anesthesiol Pharmacol & Intens Care, Geneva, Switzerland
[3] Univ Geneva, Dept Basic Neurosci, Med Sch, Geneva, Switzerland
[4] Univ Geneva, Dept Genet Med & Dev, Sch Med, Geneva, Switzerland
[5] Univ Med Ctr Gottingen, Microarray & Deep Sequencing Core Facil, Gottingen, Germany
[6] Georg August Univ Gottingen, Inst Neuropathol, D-37075 Gottingen, Germany
[7] Tech Univ Munich, Inst Neuronal Cell Biol, Munich, Germany
[8] German Ctr Neurodegenerat Dis DZNE, Munich, Germany
[9] Munich Cluster Syst Neurol SyNergy, D-81377 Munich, Germany
[10] Cedars Sinai Med Ctr, Dept Biomed Sci, Res Div Immunol, Samuel Oschin Comprehens Canc Inst, Los Angeles, CA 90048 USA
[11] Cedars Sinai Med Ctr, Dept Med, Res Div Immunol, Samuel Oschin Comprehens Canc Inst, Los Angeles, CA 90048 USA
[12] Tech Univ Munich, Sch Life Sci Weihenstephan, Div Anim Physiol & Immunol, Freising Weihenstephan, Germany
[13] Univ Basel, Dept Biomed, Haus Peterspl, Basel, Switzerland
[14] Geneva Univ Hosp, Div Clin Pathol, Geneva, Switzerland
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
SSAIO 7
引用
收藏
页码:5S / 5S
页数:1
相关论文
共 50 条
  • [41] Mycobacterium avium subspecies paratuberculosis (MAP) promotes expression of Th17 related cytokines in bovine CD4+and CD8+T cells in the presence and absence of antigen-presenting cells
    Coussens, Paul M.
    JOURNAL OF IMMUNOLOGY, 2020, 204 (01):
  • [42] Modulation of indoleamine 2, 3-dioxygenase (IDO1) expression in breast cancer cells by activated CD8+T cells is controlled by DNA promoter methylation
    Gu, F.
    Noonepalle, S. K.
    Lee, E-J
    Choi, J-H
    Shull, A. Y.
    Pei, L.
    Sreekumar, A.
    Ambs, S.
    Shi, H.
    CANCER RESEARCH, 2017, 77
  • [43] IL-21 induced Bc13 expression blocks type 1 effector differentiation of CD8+T cells and enhances their tumor efficacy
    Shrikant, Protul A.
    JOURNAL OF IMMUNOLOGY, 2009, 182
  • [44] Modulating DNA Methylation in Activated CD8+ T Cells Inhibits Regulatory T Cell-Induced Binding of Foxp3 to the CD8+ T Cell IL-2 Promoter
    Miller, Michelle M.
    Akaronu, Nnenna
    Thompson, Elizabeth M.
    Hood, Sylvia F.
    Fogle, Jonathan E.
    JOURNAL OF IMMUNOLOGY, 2015, 194 (03): : 990 - 998
  • [45] IL-12 induced Fas expression in myeloid-derived cells within tumors delivers a co-stimulatory signal for adoptively transferred CD8+T cells
    Kerkar, Sid
    Restifo, Nicholas
    JOURNAL OF IMMUNOLOGY, 2012, 188
  • [46] DNA-liposome versus adenoviral mediated gene transfer of transforming growth factorβ1 in vascularized cardiac allografts:: Differential sensitivity of CD4+and CD8+T cells to transforming growth factorβ1
    Chan, SY
    Goodman, RE
    Szmuszkovicz, JR
    Roessler, B
    Eichwald, EJ
    Bishop, DK
    TRANSPLANTATION, 2000, 70 (09) : 1292 - 1301
  • [47] Two different aspects of PD-1 expression on intrahepatic CD4+and CD8+T cells in a High Fat High Cholesterol Diet-induced murine NASH
    Yamaguchi, Kanji
    Okajima, Akira
    Seko, Yuya
    Ishiba, Hiroshi
    Taketani, Hiroyoshi
    Umemura, Atsushi
    Nishikawa, Taichiro
    Sumida, Yoshio
    Mitsuyoshi, Hironori
    Yasui, Kohichiroh
    Okanoue, Takeshi
    Itoh, Yoshito
    HEPATOLOGY, 2015, 62 : 648A - 648A
  • [48] ABNORMAL REGULATION OF THE IL-2 PROMOTER IN LPR CD4(-)CD8(-) T-LYMPHOCYTES RESULTS IN CONSTITUTIVE EXPRESSION OF A NOVEL NUCLEAR FACTOR OF ACTIVATED T-CELLS-BINDING FACTOR
    CLEMENTS, JL
    COOPER, SM
    BUDD, RC
    JOURNAL OF IMMUNOLOGY, 1995, 154 (12): : 6372 - 6381
  • [49] IL-21R expression on CDS+ T cells promotes CD8+ T cell activation in coxsackievirus B3 induced myocarditis
    Liu, Wei
    Dienz, Oliver
    Roberts, Brian
    Moussawi, Mohamad
    Rincon, Mercedes
    Huber, Sally A.
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2012, 92 (03) : 327 - 333
  • [50] Synergistic Effects Of CD4+And CD8+T Cells For The Full Development Of Allergen-Induced Airway Hyperresponsiveness Requires Leukotriene B4 Receptor-1 Expression
    Ohnishi, H.
    Miyahara, N.
    Takeda, K.
    Joetham, A.
    Yokoyama, A.
    Gelfand, E. W.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011, 183