Expression of the DNA-binding factor TOX promotes the encephalitogenic potential of microbe-induced autoreactive CD8+T cells

被引:0
|
作者
Nicolas, Page [1 ]
Bogna, Klimek [1 ]
Mathias, De Roo [2 ,3 ]
Karin, Steinbach [1 ]
Hadrien, Soldati [4 ]
Sylvain, Lemeille [1 ]
Ingrid, Wagner [1 ]
Mario, Kreutzfeldt [1 ]
Giovanni, Di Liberto [1 ]
Ilena, Vincenti [1 ]
Thomas, Lingner [5 ]
Gabriela, Salinas [5 ]
Wolfgang, Brueck [6 ]
Mikael, Simons [7 ,8 ,9 ]
Rabih, Murr [4 ]
Jonathan, Kaye [10 ,11 ]
Dietmar, Zehn [12 ]
Daniel, Pinschewer D. [13 ]
Doron, Merkler [1 ,14 ]
机构
[1] Univ Geneva, Dept Pathol & Immunol, Geneva, Switzerland
[2] Geneva Univ Hosp, Dept Anesthesiol Pharmacol & Intens Care, Geneva, Switzerland
[3] Univ Geneva, Dept Basic Neurosci, Med Sch, Geneva, Switzerland
[4] Univ Geneva, Dept Genet Med & Dev, Sch Med, Geneva, Switzerland
[5] Univ Med Ctr Gottingen, Microarray & Deep Sequencing Core Facil, Gottingen, Germany
[6] Georg August Univ Gottingen, Inst Neuropathol, D-37075 Gottingen, Germany
[7] Tech Univ Munich, Inst Neuronal Cell Biol, Munich, Germany
[8] German Ctr Neurodegenerat Dis DZNE, Munich, Germany
[9] Munich Cluster Syst Neurol SyNergy, D-81377 Munich, Germany
[10] Cedars Sinai Med Ctr, Dept Biomed Sci, Res Div Immunol, Samuel Oschin Comprehens Canc Inst, Los Angeles, CA 90048 USA
[11] Cedars Sinai Med Ctr, Dept Med, Res Div Immunol, Samuel Oschin Comprehens Canc Inst, Los Angeles, CA 90048 USA
[12] Tech Univ Munich, Sch Life Sci Weihenstephan, Div Anim Physiol & Immunol, Freising Weihenstephan, Germany
[13] Univ Basel, Dept Biomed, Haus Peterspl, Basel, Switzerland
[14] Geneva Univ Hosp, Div Clin Pathol, Geneva, Switzerland
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
SSAIO 7
引用
收藏
页码:5S / 5S
页数:1
相关论文
共 50 条
  • [31] Down-regulation of single-stranded DNA-binding protein 1 expression induced by HCMV infection promotes lipid accumulation in cells
    Guo, N.
    Zhang, N.
    Yan, L.
    Cao, X.
    Lv, F.
    Wang, J.
    Wang, Y.
    Cong, H.
    BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2017, 50 (11)
  • [32] Maturation of protective immunity induced by SIVΔnef correlates with differential expression of transcription factors in SIV-specific CD8+T cells
    Billingsley, J. M.
    Rajakumar, P. A.
    Salisch, N. C.
    Kuzmichev, Y. V.
    Hong, H. S.
    Connole, M. A.
    Reeves, R. K.
    Kang, H.
    Li, W.
    Johnson, R. P.
    RETROVIROLOGY, 2012, 9
  • [33] High PPFIA1 expression promotes cancer survival by suppressing CD8+T cells in breast cancer: drug discovery and machine learning approach
    Chu, Jinah
    Min, Kyueng-Whan
    Kim, Dong-Hoon
    Son, Byoung Kwan
    Kim, Hyung Suk
    Jung, Un Suk
    Kwon, Mi Jung
    Do, Sung-Im
    BREAST CANCER, 2023, 30 (02) : 259 - 270
  • [34] Analysis of tumor-promoting CD8+T cells reveals TH17 differentiation, regulatory capacity, and growth-factor potential
    Kwong, B.
    Roberts, S.
    Silberzahn, T.
    Filler, R.
    Galan, A.
    Neustadter, J.
    Lin, W.
    Reddy, S.
    Hayday, A.
    Girardi, M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2009, 129 : S115 - S115
  • [35] In Vivo Model to Evaluate Loss of Liver-Derived Factor IX Expression Caused by AAV Capsid-Specific CD8+T Cells
    Markusic, David M.
    Martino, Ashley T.
    Mingozzi, Federico
    High, Katherine A.
    Herzog, Roland W.
    BLOOD, 2012, 120 (21)
  • [36] Early rise in brain damage markers and high ICOS expression in CD4+and CD8+T cells during checkpoint inhibitor-induced encephalomyelitis
    Bjursten, Sara
    Pandita, Ankur
    Zhao, Zhiyuan
    Frojd, Charlotta
    Ny, Lars
    Jensen, Christer
    Ullerstam, Tobias
    Jespersen, Henrik
    Boren, Jan
    Levin, Malin
    Zetterberg, Henrik
    Rudin, Anna
    Levin, Max
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 (07)
  • [37] Oxidative stress-induced ISG15-USP18 dysregulation promotes IFN-γ secretion from CD8+T cells in vitiligo
    Lee, E.
    Kim, J.
    Park, S.
    Bae, Y.
    Kwon, I.
    Seong, S.
    Oh, S.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2023, 143 (05) : S5 - S5
  • [38] Preferential expression of αEβ7 integrin (CD103) on CD8+T cells in the psoriatic epidermis:: regulation by interleukins 4 and 12 and transforming growth factor-β
    Teraki, Y
    Shiohara, T
    BRITISH JOURNAL OF DERMATOLOGY, 2002, 147 (06) : 1118 - 1126
  • [39] Tumor necrosis factor receptor 2 promotes endothelial cell-mediated suppression of CD8+T cells through tuning glycolysis in chemoresistance of breast cancer
    Hu, Yu
    Lou, Xiaohan
    Zhang, Kaili
    Pan, Longze
    Bai, Yueyue
    Wang, Linlin
    Wang, Ming
    Yan, Yan
    Wan, Jiajia
    Yao, Xiaohan
    Duan, Xixi
    Ni, Chen
    Qin, Zhihai
    JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 22 (01)
  • [40] Therapeutic Potential of Increased Intratumoral Cytotoxic CD8+T Cells Following Antibody-Induced CTLA4 Blockade in Metastatic Melanoma
    Huang, R. R.
    Cochran, A. J.
    Ribas, A.
    LABORATORY INVESTIGATION, 2010, 90 : 116A - 116A