Field approach to three-dimensional gene expression pattern characterization -: art. no. 143901

被引：5
|
作者：
Costa, LD
Travençolo, BAN
Azeredo, A
Beletti, ME
Müller, GB
Rasskin-Gutman, D
Sternik, G
Ibañes, M
Izpisúa-Belmonte, JC
机构：
[1] Univ Sao Paulo, Inst Fis Sao Carlos, BR-13560970 Sao Carlos, SP, Brazil
[2] Univ Fed Uberlandia, Inst Ciencias Biomed, BR-38400902 Uberlandia, MG, Brazil
[3] Univ Vienna, Dept Theoret Biol, A-1090 Vienna, Austria
[4] Salk Inst Biol Studies, Gene Express Lab, La Jolla, CA 92037 USA
来源：
APPLIED PHYSICS LETTERS | 2005年 / 86卷 / 14期
基金：
巴西圣保罗研究基金会;
关键词：
D O I：
10.1063/1.1898424
中图分类号：
O59 [应用物理学];
学科分类号：
摘要：
We present a vector field method for obtaining the spatial organization of three-dimensional patterns of gene expression based on gradients and lines of force obtained by numerical integration. The convergence of these lines of force in local maxima are centers of gene expression, providing a natural and powerful framework to characterize the organization and dynamics of biological structures. We apply this methodology to analyze the expression pattern of the enhanced green fluorescent protein (EGFP) driven by the promoter of light chain myosin II during zebrafish heart formation. (C) 2005 American Institute of Physics.
引用
收藏
页码：1 / 3
页数：3
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