A conserved role for γ-tubulin as a regulator of E2F transcription factors

被引：3
作者：
Raynaud, Cecile [1 ,2 ]
Nisa, Maherun [1 ,2 ]
机构：
[1] Univ Paris Saclay, CNRS, INRAE, Univ Evry,Inst Plant Sci Paris Saclay IPS2, F-91405 Orsay, France
[2] Univ Paris, CNRS, INRAE, Inst Plant Sci Paris Saclay IPS2, F-91405 Orsay, France
来源：
JOURNAL OF EXPERIMENTAL BOTANY | 2020年 / 71卷 / 04期
关键词：
Cell cycle; development; endoreduplication; PROLIFERATION; LOCALIZATION; CYCLE;
D O I：
10.1093/jxb/erz557
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
E2F transcription factors are well known regulators of cell cycle progression in all eukaryotes. Using biochemical and genetic approaches, Kallai, Kourova and colleagues demonstrate that the microtubule nucleation factor gamma-tubulin interacts with all plant E2Fs and appear to inhibit their activity: reduced accumulation of'gamma-tubulin results in ectopic cell division in some cell types and enhanced endoreduplication in others (Kallai et al., 2020). This study reveals a microtubule-independent function of gamma-tubulin in plant cells.
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收藏
页码：1199 / 1202
页数：4
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