Facile two-step synthesis of 2-arylbenzofurans based on the selective cross McMurry couplings

被引：89

作者：

Duan, Xin-Fang ^{[1
]}

Zeng, Jing ^{[1
]}

Zhang, Zhan-Bin ^{[1
]}

Zi, Guo-Fu ^{[1
]}

机构：

[1] Beijing Normal Univ, Dept Chem, Beijing 100875, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2007年 / 72卷 / 26期

关键词：

D O I：

10.1021/jo7019652

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] A novel two-step synthesis of 2-arylbenzofurans has been developed. It involves a selective cross McMurry coupling of a salicylaldehyde or substituted salicylaldehyde with an aromatic aldehyde and a sequential oxidative cyclization of the resulting ortho-vinylphenols. Utilizing this synthetic protocol, a variety of 2-arylbenzofurans including cicerfuran (5) have been efficiently synthesized.

引用

页码：10283 / 10286

页数：4

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