USE OF ANTIMICROBIAL PHOTODYNAMIC THERAPY IN THE TREATMENT OF CHRONIC TONSILLITIS

被引：0

作者：

Yaromenka, Yuliya E. ^{[1
]}

Malets, Alena L. ^{[1
]}

Kupryianava, Hanna A. ^{[1
]}

Zburnevich, Veronika, I ^{[1
]}

Plavskii, Vitaly Y. ^{[2
]}

机构：

[1] Republican Sci & Pract Ctr Otorhinolaryngol, 8 Sukhaya Str, Minsk 220004, BELARUS

[2] Natl Acad Sci Belarus, BI Stepanov Inst Phys, 68 Nezavisimosti Ave, Minsk 220072, BELARUS

来源：

DOKLADY NATSIONALNOI AKADEMII NAUK BELARUSI | 2020年 / 64卷 / 01期

关键词：

chronic tonsillitis; chronic pharyngitis; antimicrobial photodynamic therapy; laser radiation; photosensitizers;

D O I：

10.29235/1561-8323-2020-64-1-86-93

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

An effective method for treatment of chronic tonsillitis has been developed. It is based on combined (sequential) exposure of the tonsils to laser radiation of violet (405 nm wavelength) and red (650 wavelength) spectral regions at a power density of 25 mW/cm(2) for 3 minutes for each amygdala for 7 days. It was shown that laser therapy according to the above method has positive anti-inflammatory, decongestant and antimicrobial effects. Moreover, the antimicrobial effect of laser radiation is due to the excitation of endogenous porphyrin and flavin photosensitizers, localized mainly in pathogenic microflora. The high efficiency of generation of singlet oxygen by these compounds is capable of realizing the bactericidal action of light without introducing exogenous photosensitizers.

引用

页码：86 / 93

页数：8

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