5-furan-2yl[1,3,4]oxadiazole-2-thiol, 5-furan-2yl-4H [1,2,4] triazole-3-thiol and their thiol-thione tautomerism

被引：82

作者：

Koparir, M ^{[1
]}

Çetin, A ^{[1
]}

Cansiz, A ^{[1
]}

机构：

[1] Firat Univ, Fac Sci, Dept Chem, TR-23119 Elazig, Turkey

来源：

MOLECULES | 2005年 / 10卷 / 02期

关键词：

1,3,4-oxadiazoles; 1,2,4-triazoles; Mannich bases; thiol-thione tautomerism;

D O I：

10.3390/10020475

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

5-Furan-2-yl[1,3,4]oxadiazole-2-thiol (Ia) and 5-furan-2-yl-4H-[1,2,4]triazole-3-thiol (Ib) were synthesized from furan-2-carboxylic acid hydrazide. Mannich bases and methyl derivatives were then prepared. The structures of the synthesized compounds were confirmed by elemental analyses, IR and H-1-NMR spectra. Their thiol-thione tautomeric equilibrium is described.

引用

页码：475 / 480

页数：6

共 19 条

[1]

Aydogan F, 2002, TURK J CHEM, V26, P159

[2]

BAHADUR S, 1980, J INDIAN CHEM SOC, V57, P447

[3] 1,3,4-OXADIAZOLE, 1,3,4-THIADIAZOLE, AND 1,2,4-TRIAZOLE ANALOGS OF THE FENAMATES - IN-VITRO INHIBITION OF CYCLOOXYGENASE AND 5-LIPOXYGENASE ACTIVITIES [J].

BOSCHELLI, DH ;

CONNOR, DT ;

BORNEMEIER, DA ;

DYER, RD ;

KENNEDY, JA ;

KUIPERS, PJ ;

OKONKWO, GC ;

SCHRIER, DJ ;

WRIGHT, CD .

JOURNAL OF MEDICINAL CHEMISTRY, 1993, 36 (13) :1802-1810

[4] Synthesis of some new 4,5-substituted-4H-1,2,4-triazole-3-thiol derivatives [J].

Cansiz, A ;

Koparir, M ;

Demirdag, A .

MOLECULES, 2004, 9 (04) :204-212

[5]

Cansiz A, 2001, J CHEM SOC PAKISTAN, V23, P237

[6] SYNTHESIS AND A UV AND IR SPECTRAL STUDY OF SOME 2-ARYL-DELTA(2)-1,3,4-OXADIAZOLINE-5-THIONES [J].

CHARISTOS, DA ;

VAGENAS, GV ;

TZAVELLAS, LC ;

TSOLERIDIS, CA ;

RODIOS, NA .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1994, 31 (06) :1593-1598

[7]

GIRI S, 1978, J INDIAN CHEM SOC, V55, P168

[8] SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF 1-(2,4-DICHLOROBENZOYL)-4-SUBSTITUTED THIOSEMICARBAZIDES, 1,2,4-TRIAZOLES AND THEIR METHYL-DERIVATIVES [J].

GOSWAMI, BN ;

KATAKY, JCS ;

BARUAH, JN .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1984, 21 (04) :1225-1229

[9] POLYCYCLIC N-HETERO COMPOUNDS .36. SYNTHESES AND ANTIDEPRESSIVE EVALUATION OF 11,13,15,17-TETRAAZASTEROIDS AND THEIR 17-OXIDES [J].

HIROTA, T ;

SASAKI, K ;

YAMAMOTO, H ;

NAKAYAMA, T .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1991, 28 (02) :257-261

[10] 3-Benzyl-4-(4-chlorophenyl)-1H-1,2,4-triazole-5(4H)-thione [J].

Öztürk, S ;

Akkurt, M ;

Cansiz, A ;

Koparir, M ;

Sekerci, M ;

Heinemann, FW .

ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2004, 60 :O642-O644

← 1 2 →