Accessing new chemical space for 'undruggable' targets

被引：180
作者：
Dandapani, Sivaraman
Marcaurelle, Lisa A.
机构：
来源：
NATURE CHEMICAL BIOLOGY | 2010年 / 6卷 / 12期
关键词：
DIVERSITY-ORIENTED SYNTHESIS; SMALL-MOLECULE; DISCOVERY; CHEMISTRY;
D O I：
10.1038/nchembio.479
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The synthesis and biological annotation of small molecules from underexplored chemical space will play a central role in the development of drugs for challenging targets currently being identified in frontier areas of biological research such as human genetics.
引用
收藏
页码：861 / 863
页数：4
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