Data Descriptor: FANTOM5 CAGE profiles of human and mouse reprocessed for GRCh38 and GRCm38 genome assemblies

被引:56
作者
Abugessaisa, Imad [1 ]
Noguchi, Shuhei [1 ]
Hasegawa, Akira [1 ,2 ]
Harshbarger, Jayson [1 ,2 ]
Kondo, Atsushi [1 ,2 ]
Lizio, Marina [1 ,2 ]
Severin, Jessica [1 ,2 ]
Carninci, Piero [1 ,2 ]
Kawaji, Hideya [1 ,2 ,3 ,4 ]
Kasukawa, Takeya [1 ]
机构
[1] RIKEN, Ctr Life Sci Technol, Div Genom Technol, Tsurumi Ku, 1-7-22 Suehiro Cho, Yokohama, Kanagawa 2300045, Japan
[2] RIKEN, Omics Sci Ctr, Tsurumi Ku, 1-7-22 Suehiro Cho, Yokohama, Kanagawa 2300045, Japan
[3] RIKEN, Prevent Med & Diag Innovat Program, 2-1 Hirosawa, Wako, Saitama 3510198, Japan
[4] RIKEN, Adv Ctr Comp & Commun, Prevent Med & Appl Genom Unit, Tsurumi Ku, 1-7-22 Suehiro Cho, Yokohama, Kanagawa 2300045, Japan
关键词
GENE-EXPRESSION; VISUALIZATION; BROWSER;
D O I
10.1038/sdata.2017.107
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The FANTOM5 consortium described the promoter-level expression atlas of human and mouse by using CAGE (Cap Analysis of Gene Expression) with single molecule sequencing. In the original publications, GRCh37/hg19 and NCBI37/mm9 assemblies were used as the reference genomes of human and mouse respectively; later, the Genome Reference Consortium released newer genome assemblies GRCh38/hg38 and GRCm38/mm10. To increase the utility of the atlas in forthcoming researches, we reprocessed the data to make them available on the recent genome assemblies. The data include observed frequencies of transcription starting sites (TSSs) based on the realignment of CAGE reads, and TSS peaks that are converted from those based on the previous reference. Annotations of the peak names were also updated based on the latest public databases. The reprocessed results enable us to examine frequencies of transcription initiations on the recent genome assemblies and to refer promoters with updated information across the genome assemblies consistently.
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页数:10
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