Addressing Urgent Questions for PFAS in the 21st Century

被引:114
作者
Ng, Carla [14 ,15 ]
Cousins, Ian T. [1 ]
DeWitt, Jamie C. [2 ]
Gluge, Juliane [3 ]
Goldenman, Gretta [4 ]
Herzke, Dorte [5 ,6 ]
Lohmann, Rainer [7 ]
Miller, Mark [8 ,9 ]
Patton, Sharyle [10 ]
Scheringer, Martin [3 ,11 ]
Trier, Xenia [12 ]
Wang, Zhanyun [13 ]
机构
[1] Stockholm Univ, Dept Environm Sci, SE-10691 Stockholm, Sweden
[2] East Carolina Univ, Brody Sch Med, Dept Pharmacol & Toxicol, Greenville, NC 27834 USA
[3] Swiss Fed Inst Technol, Inst Biogeochem & Pollutant Dynam, CH-8092 Zurich, Switzerland
[4] Milieu Consulting SPRL, B-1060 Brussels, Belgium
[5] Norwegian Inst Air Res NILU, N-9296 Tromso, Norway
[6] UiT Arctic Univ Norway, Inst Arctic & Marine Biol, N-9037 Tromso, Norway
[7] Univ Rhode Isl, Grad Sch Oceanog, Narragansett, RI 02882 USA
[8] NIEHS, Res Triangle Pk, NC 27709 USA
[9] US PHS, Res Triangle Pk, NC 27709 USA
[10] Commonweal, Hlth & Environm Program, Bolinas, CA 94924 USA
[11] Masaryk Univ, RECETOX, Brno 62500, Czech Republic
[12] European Environm Agcy, DK-1050 Copenhagen K, Denmark
[13] Swiss Fed Inst Technol, Chair Ecol Syst Design, Inst Environm Engn, CH-8093 Zurich, Switzerland
[14] Univ Pittsburgh, Dept Civil & Environm Engn, Pittsburgh, PA 15261 USA
[15] Univ Pittsburgh, Dept Environm & Occupat Hlth, Pittsburgh, PA 15261 USA
基金
美国国家科学基金会;
关键词
PFAS; global; health; environment; policy; equity; POLYFLUOROALKYL SUBSTANCES PFASS; DRINKING-WATER CONTAMINANTS; PERFLUOROALKYL SUBSTANCES; PERFLUORINATED COMPOUNDS; TROPHIC MAGNIFICATION; SULFLURAMID USE; SULFONIC-ACIDS; EXPOSURE; TRENDS; RIVER;
D O I
10.1021/acs.est.1c03386
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Despite decades of research on per- and polyfluoroalkyl substances (PFAS), fundamental obstacles remain to addressing worldwide contamination by these chemicals and their associated impacts on environmental quality and health. Here, we propose six urgent questions relevant to science, technology, and policy that must be tackled to address the "PFAS problem": (1) What are the global production volumes of PFAS, and where are PFAS used? (2) Where are the unknown PFAS hotspots in the environment? (3) How can we make measuring PFAS globally accessible? (4) How can we safely manage PFAScontaining waste? (5) How do we understand and describe the health effects of PFAS exposure? (6) Who pays the costs of PFAS contamination? The importance of each question and barriers to progress are briefly described, and several potential paths forward are proposed. Given the diversity of PFAS and their uses, the extreme persistence of most PFAS, the striking ongoing lack of fundamental information, and the inequity of the health and environmental impacts from PFAS contamination, there is a need for scientific and regulatory communities to work together, with cooperation from PFAS-related industries, to fill in critical data gaps and protect human health and the environment.
引用
收藏
页码:12755 / 12765
页数:11
相关论文
共 115 条
[1]   National trends in drinking water quality violations [J].
Allaire, Maura ;
Wu, Haowei ;
Lall, Upmanu .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 115 (09) :2078-2083
[2]   Population-Wide Exposure to Per- and Polyfluoroalkyl Substances from Drinking Water in the United States [J].
Andrews, David Q. ;
Naidenko, Olga, V .
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2020, 7 (12) :931-936
[3]  
[Anonymous], 1995, Toxicological profile for polycyclic aromatic hydrocarbons (PAHs)
[4]  
[Anonymous], 2004, ENCY CHEM TECHNOLOGY, V1-26
[5]  
[Anonymous], 2018, Series on Risk Management, V39, P1, DOI [10.1787/health_glance_ap-2018-en, DOI 10.1787/HEALTH_GLANCE_AP-2018-EN]
[6]  
[Anonymous], SAF CHOIC
[7]   Treatment of poly- and perfluoroalkyl substances in US full-scale water treatment systems [J].
Appleman, Timothy D. ;
Higgins, Christopher P. ;
Quinones, Oscar ;
Vanderford, Brett J. ;
Kolstad, Chad ;
Zeigler-Holady, Janie C. ;
Dickenson, Eric R. V. .
WATER RESEARCH, 2014, 51 :246-255
[8]   Modeling the Global Fate and Transport of Perfluorooctanoic Acid (PFOA) and Perfluorooctanoate (PFO) Emitted from Direct Sources Using a Multispecies Mass Balance Model [J].
Armitage, James M. ;
MacLeod, Matthew ;
Cousins, Ian T. .
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2009, 43 (04) :1134-1140
[9]   Emerging per- and polyfluoroalkyl substances (PFAS) in human milk from Sweden and China [J].
Awad, Raed ;
Zhou, Yihui ;
Nyberg, Elisabeth ;
Namazkar, Shahla ;
Yongning, Wu ;
Xiao, Qianfen ;
Sun, Yaije ;
Zhu, Zhiliang ;
Bergman, Ake ;
Benskin, Jonathan P. .
ENVIRONMENTAL SCIENCE-PROCESSES & IMPACTS, 2020, 22 (10) :2023-2030
[10]  
Baker A. C., 2020, 3727550 SSRN