Balamuthia mandrillaris Granulomatous Amoebic Encephalitis: The First African Experience

被引：5
作者：
Tootla, Hafsah D. [1 ,2 ]
Eley, Brian S. [2 ,3 ,4 ]
Enslin, Johannes M. N. [4 ,5 ]
Frean, John A. [6 ,7 ]
Hlela, Carol [4 ,8 ]
Kilborn, Tracy N. [4 ,9 ]
Moodley, Bhavani [6 ]
Peer, Shazia [4 ,10 ]
Singh, Shivani [11 ]
Nuttall, James J. C. [2 ,3 ,4 ]
机构：
[1] Red Cross War Mem Childrens Hosp, Div Med Microbiol, Natl Hlth Lab Serv, Cape Town, South Africa
[2] Univ Cape Town, Cape Town, South Africa
[3] Univ Cape Town, Dept Paediat & Child Hlth, Paediat Infect Dis Unit, Cape Town, South Africa
[4] Red Cross War Mem Childrens Hosp, Cape Town, South Africa
[5] Univ Cape Town, Dept Surg, Div Neurosurg, Cape Town, South Africa
[6] Natl Inst Communicable Dis, Ctr Emerging Zoonot & Parasit Dis, Div Natl Hlth Lab Serv, Johannesburg, South Africa
[7] Univ Witwatersrand, Wits Res Inst Malaria, Johannesburg, South Africa
[8] Univ Cape Town, Dept Paediat & Child Hlth, Paediat Dermatol Unit, Cape Town, South Africa
[9] Univ Cape Town, Dept Radiol, Div Paediat Radiol, Cape Town, South Africa
[10] Univ Cape Town, Div Otolaryngol, Dept Surg, Cape Town, South Africa
[11] Red Cross War Mem Childrens Hosp, Div Anat Pathol, Natl Hlth Lab Serv, Cape Town, South Africa
来源：
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY | 2022年 / 11卷 / 12期
关键词：
Balamuthia mandrillaris; free-living amoebae; granulomatous amoebic encephalitis; miltefosine; spinal cord; MENINGOENCEPHALITIS;
D O I：
10.1093/jpids/piac096
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
We report the first case of Balamuthia mandrillaris granulomatous amoebic encephalitis definitively acquired in Africa. Our case emphasizes initial nonspecific dermatological features, delays in confirmation of the diagnosis, difficulties accessing recommended medication, and uncertainty about optimal treatment of a disease with a frequently fatal outcome.
引用
收藏
页码：578 / 581
页数：4
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