Dietary carbohydrate restriction in type 2 diabetes mellitus and metabolic syndrome: time for a critical appraisal

被引：180

作者：

Accurso, Anthony ^{[1
]}

Bernstein, Richard K. ^{[2
]}

Dahlqvist, Annika ^{[3
]}

Draznin, Boris ^{[4
]}

Feinman, Richard D. ^{[1
]}

Fine, Eugene J. ^{[5
]}

Gleed, Amy ^{[1
]}

Jacobs, David B. ^{[1
]}

Larson, Gabriel ^{[1
]}

Lustig, Robert H. ^{[6
]}

Manninen, Anssi H. ^{[7
]}

McFarlane, Samy I. ^{[1
]}

Morrison, Katharine ^{[8
]}

Nielsen, Jorgen Vesti ^{[9
]}

Ravnskov, Uffe ^{[10
]}

Roth, Karl S. ^{[11
]}

Silvestre, Ricardo ^{[12
]}

Sowers, James R. ^{[13
]}

Sundberg, Ralf ^{[14
]}

Volek, Jeff S. ^{[15
]}

Westman, Eric C. ^{[16
]}

Wood, Richard J. ^{[17
]}

Wortman, Jay ^{[18
]}

Vernon, Mary C. ^{[19
]}

机构：

[1] SUNY Hlth Sci Ctr, Brooklyn, NY 11203 USA

[2] New York Diabet Ctr, Mamaroneck, NY USA

[3] Privatr Practice, Njurunda, Sweden

[4] Univ Colorado, Hlth Sci Ctr, Denver, CO USA

[5] Albert Einstein Coll Med, Bronx, NY 10467 USA

[6] Univ Calif San Francisco, Med Ctr, Div Pediat Endocrinol, San Francisco, CA 94143 USA

[7] Manninen Nutraceut Oy, Oulu, Finland

[8] Ballochmyle Med Grp, Mauchline, Ayr, Scotland

[9] Cty Hosp, Karlshamn, Sweden

[10] Independent Res, Lund, Sweden

[11] Creighton Univ, Dept Pediat, Omaha, NE 68178 USA

[12] Portuguese Sports Inst, Cruz Quebrada, Portugal

[13] Univ Missouri, Cosmopolitan Int Diabet Ctr, Columbia, MO USA

[14] Slottsstadens Lakarhus, Malmo, Sweden

[15] Univ Connecticut, Dept Kinesiol, Storrs, CT USA

[16] Duke Univ, Med Ctr, Lifestyle Med Clin, Durham, NC USA

[17] Springfield Coll, Springfield, MA USA

[18] Hlth Canada, Natl Div 1, Vancouver, BC, Canada

[19] Private Practice, Lawrence, KS USA

来源：

NUTRITION & METABOLISM | 2008年 / 5卷 / 1期

关键词：

D O I：

10.1186/1743-7075-5-9

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Current nutritional approaches to metabolic syndrome and type 2 diabetes generally rely on reductions in dietary fat. The success of such approaches has been limited and therapy more generally relies on pharmacology. The argument is made that a re-evaluation of the role of carbohydrate restriction, the historical and intuitive approach to the problem, may provide an alternative and possibly superior dietary strategy. The rationale is that carbohydrate restriction improves glycemic control and reduces insulin fluctuations which are primary targets. Experiments are summarized showing that carbohydrate-restricted diets are at least as effective for weight loss as low-fat diets and that substitution of fat for carbohydrate is generally beneficial for risk of cardiovascular disease. These beneficial effects of carbohydrate restriction do not require weight loss. Finally, the point is reiterated that carbohydrate restriction improves all of the features of metabolic syndrome.

引用

页数：8

共 64 条

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