Human to mosquito transmiss on of dengue viruses

被引:115
作者
Carrington, Lauren B. [1 ,2 ]
Simmons, Cameron P. [1 ,2 ,3 ]
机构
[1] Univ Oxford, Hosp Trop Dis, Clin Res Unit, Dengue Grp, Ho Chi Minh City, Vietnam
[2] Univ Melbourne, Dept Microbiol & Immunol, Melbourne, Vic, Australia
[3] Univ Oxford, Ctr Trop Med, Nuffield Dept Clin Med, Oxford, England
基金
英国医学研究理事会;
关键词
dengue virus; transmission; Aedes aegypti; Aedes albopictus; viral titer; temperature; symptomatic vs. asymptomatic infections; AEDES STEGOMYIA ALBOPICTUS; BLOOD-FEEDING BEHAVIOR; DIPTERA-CULICIDAE; VECTOR COMPETENCE; GLOBAL DISTRIBUTION; ECONOMIC BURDEN; AEGYPTI DIPTERA; 1ST RECORD; INFECTION; TEMPERATURE;
D O I
10.3389/fimmu.2014.00290
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The successful transmission of dengue virus from a human host to a mosquito vector requires a complex set of factors to align. It is becoming increasingly important to improve our understanding of the parameters that shape the human to mosquito component of the transmission cycle so that vaccines and therapeutic antivirals can be fully evaluated and epidemiological models refined. Here we describe these factors, and discuss the biological and environmental impacts and demographic changes that are influencing these dynamics. Specifically, we examine features of the human infection required for the mosquito to acquire the virus via natural blood feeding, as well as the biological and environmental factors that influence a mosquito's susceptibility to infection, up to the point that they are capable of transmitting the virus to a new host.
引用
收藏
页数:8
相关论文
共 82 条
[1]  
Adhami J, 1998, J AM MOSQUITO CONTR, V14, P340
[2]   Dengue in travellers is still underestimated [J].
Allwinn, Regina ;
Hofknecht, Nina ;
Doerr, Hans Wilhelm .
INTERVIROLOGY, 2008, 51 (02) :96-100
[3]  
Alves MJ, 2013, EUROSURVEILLANCE, V18
[4]   Epidemiological Factors Associated with Dengue Shock Syndrome and Mortality in Hospitalized Dengue Patients in Ho Chi Minh City, Vietnam [J].
Anders, Katherine L. ;
Nguyen Minh Nguyet ;
Nguyen Van Vinh Chau ;
Nguyen Thanh Hung ;
Tran Thi Thuy ;
Le Bich Lien ;
Jeremy Farrar ;
Bridget Wills ;
Tran Tinh Hien ;
Simmons, Cameron P. .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2011, 84 (01) :127-134
[5]   Differential Susceptibility of Aedes aegypti to Infection by the American and Southeast Asian Genotypes of Dengue Type 2 Virus [J].
Armstrong, Philip ;
Rico-Hesse, Rebeca .
VECTOR-BORNE AND ZOONOTIC DISEASES, 2001, 1 (02) :159-+
[6]   Experimental investigations regarding the etiology of dengue fever [J].
Ashburn, PM ;
Craig, CF .
JOURNAL OF INFECTIOUS DISEASES, 1907, 4 (03) :440-475
[7]   Cost and disease burden of Dengue in Cambodia [J].
Beaute, Julien ;
Vong, Sirenda .
BMC PUBLIC HEALTH, 2010, 10 :521
[8]   Early detection of dengue infections using cluster sampling around index cases [J].
Beckett, CG ;
Kosasih, H ;
Faisal, I ;
Nurhayati ;
Tan, R ;
Widjaja, S ;
Listiyaningsih, E ;
Ma'Roef, C ;
Wuryadi, S ;
Bangs, MJ ;
Samsi, TK ;
Yuwono, D ;
Hayes, CG ;
Porter, KR .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2005, 72 (06) :777-782
[9]   Australia's Dengue Risk Driven by Human Adaptation to Climate Change [J].
Beebe, Nigel W. ;
Cooper, Robert D. ;
Mottram, Pipi ;
Sweeney, Anthony W. .
PLOS NEGLECTED TROPICAL DISEASES, 2009, 3 (05)
[10]   Spread of the tiger:: Global risk of invasion by the mosquito Aedes albopictus [J].
Benedict, Mark Q. ;
Levine, Rebecca S. ;
Hawley, William A. ;
Lounibos, L. Philip .
VECTOR-BORNE AND ZOONOTIC DISEASES, 2007, 7 (01) :76-85