Molecular imaging of stem cells for the treatment of acute myocardial infarction

被引：0

作者：

Li, Xiao

Wang, Yi-Ning ^{[1
,2
]}

Jin, Zheng-Yu

机构：

[1] CAMS, PUMC Hosp, Dept Radiol, 1 Shuaifuyuan, Beijing 100730, Peoples R China

[2] PUMC, Beijing 100730, Peoples R China

来源：

INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2015年 / 8卷 / 06期

基金：

中国国家自然科学基金;

关键词：

Molecular imaging; stem cell therapy; acute myocardial infarction; CARDIOSPHERE-DERIVED CELLS; LEFT-VENTRICULAR FUNCTION; FUNCTIONAL IMPROVEMENT; THERAPY; HEART; ENGRAFTMENT; SURVIVAL; DIFFERENTIATION; INFUSION; RECOVERY;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Stem cell therapy has a unique potential and promises hope for the treatment of acute myocardial infarction. Preclinical studies have identified barriers to clinical translation, one of which involves the monitoring of transplanted cells and the elucidation of their fates in vivo. Molecular imaging may help the solutions for these challenges. In this review, we illustrate the mechanisms by which molecular imaging enables insights into and the development of stem cell therapy.

引用

页码：8938 / 8947

页数：10

共 49 条

[21] Regenerative Cell Imaging in Cardiac Repair [J].

Moudgil, Rohit ;

Dick, Alexander J. .

CANADIAN JOURNAL OF CARDIOLOGY, 2014, 30 (11) :1323-1334

[22] Stem Cell Imaging: From Bench to Bedside [J].

Nguyen, Patricia K. ;

Riegler, Johannes ;

Wu, Joseph C. .

CELL STEM CELL, 2014, 14 (04) :431-444

[23] Longitudinal Bioluminescence Imaging of the Dynamics of Doxorubicin Induced Apoptosis [J].

Niu, Gang ;

Zhu, Lei ;

Ho, Don N. ;

Zhang, Fan ;

Gao, Haokao ;

Quan, Qimeng ;

Hida, Naoki ;

Ozawa, Takeaki ;

Liu, Gang ;

Chen, Xiaoyuan .

THERANOSTICS, 2013, 3 (03) :190-200

[24] Targeting of Herpes Simplex Virus 1 Thymidine Kinase Gene Sequences into the OCT4 Locus of Human Induced Pluripotent Stem Cells [J].

Ou, Wu ;

Li, Pingjuan ;

Reiser, Jakob .

PLOS ONE, 2013, 8 (11)

[25] Embryonic Cardiomyocyte, but Not Autologous Stem Cell Transplantation, Restricts Infarct Expansion, Enhances Ventricular Function, and Improves Long-Term Survival [J].

Paulis, Leonie E. ;

Klein, Alexandra M. ;

Ghanem, Alexander ;

Geelen, Tessa ;

Coolen, Bram F. ;

Breitbach, Martin ;

Zimmermann, Katrin ;

Nicolay, Klaas ;

Fleischmann, Bernd K. ;

Roell, Wilhelm ;

Strijkers, Gustav J. .

PLOS ONE, 2013, 8 (04)

[26] Multimodality Molecular Imaging to Monitor Transplanted Stem Cells for the Treatment of Ischemic Heart Disease [J].

Pei, Zhijun ;

Lan, Xiaoli ;

Cheng, Zhen ;

Qin, Chunxia ;

Xia, Xiaotian ;

Yuan, Hui ;

Ding, Zhiling ;

Zhang, Yongxue .

PLOS ONE, 2014, 9 (03)

[27]

Penheiter AR, 2012, CURR GENE THER, V12, P33

[28] Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells on Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure The FOCUS-CCTRN Trial [J].

Perin, Emerson C. ;

Willerson, James T. ;

Pepine, Carl J. ;

Henry, Timothy D. ;

Ellis, Stephen G. ;

Zhao, David X. M. ;

Silva, Guilherme V. ;

Lai, Dejian ;

Thomas, James D. ;

Kronenberg, Marvin W. ;

Martin, A. Daniel ;

Anderson, R. David ;

Traverse, Jay H. ;

Penn, Marc S. ;

Anwaruddin, Saif ;

Hatzopoulos, Antonis K. ;

Gee, Adrian P. ;

Taylor, Doris A. ;

Cogle, Christopher R. ;

Smith, Deirdre ;

Westbrook, Lynette ;

Chen, James ;

Handberg, Eileen ;

Olson, Rachel E. ;

Geither, Carrie ;

Bowman, Sherry ;

Francescon, Judy ;

Baraniuk, Sarah ;

Piller, Linda B. ;

Simpson, Lara M. ;

Loghin, Catalin ;

Aguilar, David ;

Richman, Sara ;

Zierold, Claudia ;

Bettencourt, Judy ;

Sayre, Shelly L. ;

Vojvodic, Rachel W. ;

Skarlatos, Sonia I. ;

Gordon, David J. ;

Ebert, Ray F. ;

Kwak, Minjung ;

Moye, Lemuel A. ;

Simari, Robert D. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2012, 307 (16) :1717-1726

[29] Application of stem cell/growth factor system, as a multimodal therapy approach in regenerative medicine to improve cell therapy yields [J].

Pourrajab, Fatemeh ;

Zarch, Mojtaba Babaei ;

Yazdi, Mohammad Baghi ;

Zarchi, Abolfazl Rahimi ;

Zarch, Abbas Vakili .

INTERNATIONAL JOURNAL OF CARDIOLOGY, 2014, 173 (01) :12-19

[30] CD34+ cell infusion after ST elevation myocardial infarction is associated with improved perfusion and is dose dependent [J].

Quyyumi, Arshed A. ;

Waller, Edmund K. ;

Murrow, Jonathan ;

Esteves, Fabio ;

Galt, James ;

Oshinski, John ;

Lerakis, Stamatios ;

Sher, Salman ;

Vaughan, Douglas ;

Perin, Emerson ;

Willerson, James ;

Kereiakes, Dean ;

Gersh, Bernard J. ;

Gregory, Douglas ;

Werner, Astrid ;

Moss, Thomas ;

Chan, Wai Shun ;

Preti, Robert ;

Pecora, Andrew L. .

AMERICAN HEART JOURNAL, 2011, 161 (01) :98-105

← 1 2 3 4 5 →