Molecular imaging of stem cells for the treatment of acute myocardial infarction

被引：0
作者：
Li, Xiao
Wang, Yi-Ning [1 ,2 ]
Jin, Zheng-Yu
机构：
[1] CAMS, PUMC Hosp, Dept Radiol, 1 Shuaifuyuan, Beijing 100730, Peoples R China
[2] PUMC, Beijing 100730, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE | 2015年 / 8卷 / 06期
基金：
中国国家自然科学基金;
关键词：
Molecular imaging; stem cell therapy; acute myocardial infarction; CARDIOSPHERE-DERIVED CELLS; LEFT-VENTRICULAR FUNCTION; FUNCTIONAL IMPROVEMENT; THERAPY; HEART; ENGRAFTMENT; SURVIVAL; DIFFERENTIATION; INFUSION; RECOVERY;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Stem cell therapy has a unique potential and promises hope for the treatment of acute myocardial infarction. Preclinical studies have identified barriers to clinical translation, one of which involves the monitoring of transplanted cells and the elucidation of their fates in vivo. Molecular imaging may help the solutions for these challenges. In this review, we illustrate the mechanisms by which molecular imaging enables insights into and the development of stem cell therapy.
引用
收藏
页码：8938 / 8947
页数：10
相关论文
共 49 条
[1]   Cell Therapy with Embryonic Stem Cell-Derived Cardiomyocytes Encapsulated in Injectable Nanomatrix Gel Enhances Cell Engraftment and Promotes Cardiac Repair [J].
Ban, Kiwon ;
Park, Hun-Jun ;
Kim, Sangsung ;
Andukuri, Adinarayana ;
Cho, Kyu-Won ;
Hwang, Jung Wook ;
Cha, Ho Jin ;
Kim, Sang Yoon ;
Kim, Woan-Sang ;
Jun, Ho-Wook ;
Yoon, Young-Sup .
ACS NANO, 2014, 8 (10) :10815-10825
[2]   Efficient Differentiation of Human Induced Pluripotent Stem Cells Generates Cardiac Cells That Provide Protection Following Myocardial Infarction in the Rat [J].
Carpenter, Lee ;
Carr, Carolyn ;
Yang, Cheng Tao ;
Stuckey, Daniel J. ;
Clarke, Kieran ;
Watt, Suzanne M. .
STEM CELLS AND DEVELOPMENT, 2012, 21 (06) :977-986
[3]   Molecular imaging: The key to advancing cardiac stem cell therapy [J].
Chen, Ian Y. ;
Wu, Joseph C. .
TRENDS IN CARDIOVASCULAR MEDICINE, 2013, 23 (06) :201-210
[4]   Relative Roles of Direct Regeneration Versus Paracrine Effects of Human Cardiosphere-Derived Cells Transplanted Into Infarcted Mice [J].
Chimenti, Isotta ;
Smith, Rachel Ruckdeschel ;
Li, Tao-Sheng ;
Gerstenblith, Gary ;
Messina, Elisa ;
Giacomello, Alessandro ;
Marban, Eduardo .
CIRCULATION RESEARCH, 2010, 106 (05) :971-U304
[5]   Long-Term Effects of Autologous Bone Marrow Stem Cell Treatment in Acute Myocardial Infarction: Factors That May Influence Outcomes [J].
Clifford, David M. ;
Fisher, Sheila A. ;
Brunskill, Susan J. ;
Doree, Carolyn ;
Mathur, Anthony ;
Clarke, Mike J. ;
Watt, Suzanne M. ;
Martin-Rendon, Enca .
PLOS ONE, 2012, 7 (05)
[6]   Intracoronary Stem Cell Infusion After Acute Myocardial Infarction A Meta-Analysis and Update on Clinical Trials [J].
de Jong, Renate ;
Houtgraaf, Jaco H. ;
Samiei, Sanaz ;
Boersma, Eric ;
Duckers, Henricus J. .
CIRCULATION-CARDIOVASCULAR INTERVENTIONS, 2014, 7 (02) :156-+
[7]   Bone-Derived Stem Cells Repair the Heart After Myocardial Infarction Through Transdifferentiation and Paracrine Signaling Mechanisms [J].
Duran, Jason M. ;
Makarewich, Catherine A. ;
Sharp, Thomas E. ;
Starosta, Timothy ;
Zhu, Fang ;
Hoffman, Nicholas E. ;
Chiba, Yumi ;
Madesh, Muniswamy ;
Berretta, Remus M. ;
Kubo, Hajime ;
Houser, Steven R. .
CIRCULATION RESEARCH, 2013, 113 (05) :539-552
[8]   Assessment of three techniques for delivering stem cells to the heart using PET and MR imaging [J].
Elhami, Esmat ;
Dietz, Bryson ;
Xiang, Bo ;
Deng, Jixian ;
Wang, Fei ;
Chi, Chao ;
Goertzen, Andrew L. ;
Mzengeza, Shadreck ;
Freed, Darren ;
Arora, Rakesh C. ;
Tian, Ganghong .
EJNMMI RESEARCH, 2013, 3 :1-11
[9]   Prompt Bone Marrow-Derived Mesenchymal Stem Cell Therapy Enables Early Porcine Heart Function Recovery From Acute Myocardial Infarction Evaluation Using Magnetic Resonance Imaging and Molecular-Cellular Signaling [J].
Fan, Chang-Qing ;
Leu, Steve ;
Sheu, Jiunn-Jye ;
Zhen, Yen-Yi ;
Tsai, Tzu-Hsien ;
Chen, Yung-Lung ;
Chung, Sheng-Ying ;
Chai, Han-Tan ;
Sun, Cheuk-Kwan ;
Yang, Jenq-Lin ;
Chang, Hsueh-Wen ;
Ko, Sheung-Fat ;
Yip, Hon-Kan .
INTERNATIONAL HEART JOURNAL, 2014, 55 (04) :362-371
[10]   Intracoronary Infusion of Allogeneic Mesenchymal Precursor Cells Directly After Experimental Acute Myocardial Infarction Reduces Infarct Size, Abrogates Adverse Remodeling, and Improves Cardiac Function [J].
Houtgraaf, Jaco H. ;
de Jong, Renate ;
Kazemi, Kushan ;
de Groot, Daphne ;
van der Spoel, Tycho I. G. ;
Arslan, Fatih ;
Hoefer, Imo ;
Pasterkamp, Gerard ;
Itescu, Silviu ;
Zijlstra, Felix ;
Geleijnse, Marcel L. ;
Serruys, Patrick W. ;
Duckers, Henricus J. .
CIRCULATION RESEARCH, 2013, 113 (02) :153-166
12345