SYNTHESIS OF NAPHTHO[2,1-b]PYRANO PYRROLOTHIAZOLE DERIVATIVES THROUGH 1,3-CYCLOADDITION REACTION

被引：2

作者：

Kathiravan, Subban ^{[1
]}

Raghunathan, Raghavachary ^{[1
]}

机构：

[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 20期

关键词：

Azomethine ylides; Baylis-Hillman adduct; 1,3-dipolar cycloaddition; pyrrolothiazoles; BAYLIS-HILLMAN REACTION;

D O I：

10.1080/00397911.2011.575523

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Facile synthesis of a series of naphtho[2,1,b]pyrano pyrrolo thiazoles was accomplished in good yields in a one-pot reaction through intramolecular 1,3-dipolar cycloaddition of cyclic azomethine ylides with Baylis-Hillman adducts as dipolarophiles. The protocol is applicable to a wide variety of photochromic and biologically active naptho-pyrano products. The regio- and stereochemical outcome of the cycloaddition reaction was ascertained by x-ray crystallographic study of one of the cycloadducts.

引用

页码：3068 / 3076

页数：9

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